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mTOR plays a critical role in p53-induced oxidative kidney cell injury in HIVAN.
Rai P, Plagov A, Lan X, Chandel N, Singh T, Lederman R, Ayasolla KR, Mathieson PW, Saleem MA, Husain M, Malhotra A, Chander PN, Singhal PC. Rai P, et al. Among authors: singhal pc. Am J Physiol Renal Physiol. 2013 Aug 1;305(3):F343-54. doi: 10.1152/ajprenal.00135.2013. Epub 2013 May 15. Am J Physiol Renal Physiol. 2013. PMID: 23678040 Free PMC article.
Tenofovir-induced kidney injury.
Gitman MD, Hirschwerk D, Baskin CH, Singhal PC. Gitman MD, et al. Among authors: singhal pc. Expert Opin Drug Saf. 2007 Mar;6(2):155-64. doi: 10.1517/14740338.6.2.155. Expert Opin Drug Saf. 2007. PMID: 17367261
Aldosterone induces mesangial cell apoptosis both in vivo and in vitro.
Mathew JT, Patni H, Chaudhary AN, Liang W, Gupta A, Chander PN, Ding G, Singhal PC. Mathew JT, et al. Among authors: singhal pc. Am J Physiol Renal Physiol. 2008 Jul;295(1):F73-81. doi: 10.1152/ajprenal.00435.2007. Epub 2008 May 7. Am J Physiol Renal Physiol. 2008. PMID: 18463316 Free PMC article.
Inhibition of p66ShcA longevity gene rescues podocytes from HIV-1-induced oxidative stress and apoptosis.
Husain M, Meggs LG, Vashistha H, Simoes S, Griffiths KO, Kumar D, Mikulak J, Mathieson PW, Saleem MA, Del Valle L, Pina-Oviedo S, Wang JY, Seshan SV, Malhotra A, Reiss K, Singhal PC. Husain M, et al. Among authors: singhal pc. J Biol Chem. 2009 Jun 12;284(24):16648-16658. doi: 10.1074/jbc.M109.008482. Epub 2009 Apr 21. J Biol Chem. 2009. PMID: 19383602 Free PMC article.
Human immunodeficiency virus downregulates podocyte apoE expression.
Arora S, Husain M, Kumar D, Patni H, Pathak S, Mehrotra D, Reddy VK, Reddy LR, Salhan D, Yadav A, Mathieson PW, Saleem MA, Chander PN, Singhal PC. Arora S, et al. Among authors: singhal pc. Am J Physiol Renal Physiol. 2009 Sep;297(3):F653-61. doi: 10.1152/ajprenal.90668.2008. Epub 2009 Jun 24. Am J Physiol Renal Physiol. 2009. PMID: 19553347 Free PMC article.
HIVAN phenotype: consequence of epithelial mesenchymal transdifferentiation.
Yadav A, Vallabu S, Kumar D, Ding G, Charney DN, Chander PN, Singhal PC. Yadav A, et al. Among authors: singhal pc. Am J Physiol Renal Physiol. 2010 Mar;298(3):F734-44. doi: 10.1152/ajprenal.00415.2009. Epub 2009 Dec 16. Am J Physiol Renal Physiol. 2010. PMID: 20015943 Free PMC article.
HIV-associated nephropathy: role of mammalian target of rapamycin pathway.
Kumar D, Konkimalla S, Yadav A, Sataranatarajan K, Kasinath BS, Chander PN, Singhal PC. Kumar D, et al. Among authors: singhal pc. Am J Pathol. 2010 Aug;177(2):813-21. doi: 10.2353/ajpath.2010.100131. Epub 2010 Jun 25. Am J Pathol. 2010. PMID: 20581056 Free PMC article.
316 results