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86 results

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Page 1
Pharmacologic activation of PKM2 slows lung tumor xenograft growth.
Parnell KM, Foulks JM, Nix RN, Clifford A, Bullough J, Luo B, Senina A, Vollmer D, Liu J, McCarthy V, Xu Y, Saunders M, Liu XH, Pearce S, Wright K, O'Reilly M, McCullar MV, Ho KK, Kanner SB. Parnell KM, et al. Among authors: kanner sb. Mol Cancer Ther. 2013 Aug;12(8):1453-60. doi: 10.1158/1535-7163.MCT-13-0026. Epub 2013 May 29. Mol Cancer Ther. 2013. PMID: 23720766
Epigenetic drug discovery: targeting DNA methyltransferases.
Foulks JM, Parnell KM, Nix RN, Chau S, Swierczek K, Saunders M, Wright K, Hendrickson TF, Ho KK, McCullar MV, Kanner SB. Foulks JM, et al. Among authors: kanner sb. J Biomol Screen. 2012 Jan;17(1):2-17. doi: 10.1177/1087057111421212. Epub 2011 Sep 30. J Biomol Screen. 2012. PMID: 21965114 Review.
An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance.
Byers LA, Diao L, Wang J, Saintigny P, Girard L, Peyton M, Shen L, Fan Y, Giri U, Tumula PK, Nilsson MB, Gudikote J, Tran H, Cardnell RJ, Bearss DJ, Warner SL, Foulks JM, Kanner SB, Gandhi V, Krett N, Rosen ST, Kim ES, Herbst RS, Blumenschein GR, Lee JJ, Lippman SM, Ang KK, Mills GB, Hong WK, Weinstein JN, Wistuba II, Coombes KR, Minna JD, Heymach JV. Byers LA, et al. Among authors: kanner sb. Clin Cancer Res. 2013 Jan 1;19(1):279-90. doi: 10.1158/1078-0432.CCR-12-1558. Epub 2012 Oct 22. Clin Cancer Res. 2013. PMID: 23091115 Free PMC article.
Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors.
Ho KK, Parnell KM, Yuan Y, Xu Y, Kultgen SG, Hamblin S, Hendrickson TF, Luo B, Foulks JM, McCullar MV, Kanner SB. Ho KK, et al. Among authors: kanner sb. Bioorg Med Chem Lett. 2013 Jan 15;23(2):569-73. doi: 10.1016/j.bmcl.2012.11.013. Epub 2012 Nov 16. Bioorg Med Chem Lett. 2013. PMID: 23232060
A small-molecule inhibitor of PIM kinases as a potential treatment for urothelial carcinomas.
Foulks JM, Carpenter KJ, Luo B, Xu Y, Senina A, Nix R, Chan A, Clifford A, Wilkes M, Vollmer D, Brenning B, Merx S, Lai S, McCullar MV, Ho KK, Albertson DJ, Call LT, Bearss JJ, Tripp S, Liu T, Stephens BJ, Mollard A, Warner SL, Bearss DJ, Kanner SB. Foulks JM, et al. Among authors: kanner sb. Neoplasia. 2014 May;16(5):403-12. doi: 10.1016/j.neo.2014.05.004. Epub 2014 Jun 18. Neoplasia. 2014. PMID: 24953177 Free PMC article.
HIF2α-Targeted RNAi Therapeutic Inhibits Clear Cell Renal Cell Carcinoma.
Wong SC, Cheng W, Hamilton H, Nicholas AL, Wakefield DH, Almeida A, Blokhin AV, Carlson J, Neal ZC, Subbotin V, Zhang G, Hegge J, Bertin S, Trubetskoy VS, Rozema DB, Lewis DL, Kanner SB. Wong SC, et al. Among authors: kanner sb. Mol Cancer Ther. 2018 Jan;17(1):140-149. doi: 10.1158/1535-7163.MCT-17-0471. Epub 2017 Oct 27. Mol Cancer Ther. 2018. PMID: 29079709
Monoclonal antibodies to six-transmembrane epithelial antigen of the prostate-1 inhibit intercellular communication in vitro and growth of human tumor xenografts in vivo.
Challita-Eid PM, Morrison K, Etessami S, An Z, Morrison KJ, Perez-Villar JJ, Raitano AB, Jia XC, Gudas JM, Kanner SB, Jakobovits A. Challita-Eid PM, et al. Among authors: kanner sb. Cancer Res. 2007 Jun 15;67(12):5798-805. doi: 10.1158/0008-5472.CAN-06-3849. Cancer Res. 2007. PMID: 17575147
86 results