Brekken RA - Search Results

1

BIBF 1120 (nintedanib), a triple angiokinase inhibitor, induces hypoxia but not EMT and blocks progression of preclinical models of lung and pancreatic cancer.

Kutluk Cenik B, Ostapoff KT, Gerber DE, Brekken RA. Kutluk Cenik B, et al. Among authors: brekken ra. Mol Cancer Ther. 2013 Jun;12(6):992-1001. doi: 10.1158/1535-7163.MCT-12-0995. Epub 2013 May 31. Mol Cancer Ther. 2013. PMID: 23729403 Free PMC article.

2

Molecular consequences of silencing mutant K-ras in pancreatic cancer cells: justification for K-ras-directed therapy.

Fleming JB, Shen GL, Holloway SE, Davis M, Brekken RA. Fleming JB, et al. Among authors: brekken ra. Mol Cancer Res. 2005 Jul;3(7):413-23. doi: 10.1158/1541-7786.MCR-04-0206. Mol Cancer Res. 2005. PMID: 16046552

3

Selective blockade of vascular endothelial growth factor receptor 2 with an antibody against tumor-derived vascular endothelial growth factor controls the growth of human pancreatic adenocarcinoma xenografts.

Holloway SE, Beck AW, Shivakumar L, Shih J, Fleming JB, Brekken RA. Holloway SE, et al. Among authors: brekken ra. Ann Surg Oncol. 2006 Aug;13(8):1145-55. doi: 10.1245/ASO.2006.05.049. Epub 2006 Jun 21. Ann Surg Oncol. 2006. PMID: 16791450

4

Monitoring response to anticancer therapy by targeting microbubbles to tumor vasculature.

Korpanty G, Carbon JG, Grayburn PA, Fleming JB, Brekken RA. Korpanty G, et al. Among authors: brekken ra. Clin Cancer Res. 2007 Jan 1;13(1):323-30. doi: 10.1158/1078-0432.CCR-06-1313. Clin Cancer Res. 2007. PMID: 17200371

5

Vascular endothelial growth factor receptor 2 mediates macrophage infiltration into orthotopic pancreatic tumors in mice.

Dineen SP, Lynn KD, Holloway SE, Miller AF, Sullivan JP, Shames DS, Beck AW, Barnett CC, Fleming JB, Brekken RA. Dineen SP, et al. Among authors: brekken ra. Cancer Res. 2008 Jun 1;68(11):4340-6. doi: 10.1158/0008-5472.CAN-07-6705. Cancer Res. 2008. PMID: 18519694

6

Semaphorin 3B inhibits the phosphatidylinositol 3-kinase/Akt pathway through neuropilin-1 in lung and breast cancer cells.

Castro-Rivera E, Ran S, Brekken RA, Minna JD. Castro-Rivera E, et al. Among authors: brekken ra. Cancer Res. 2008 Oct 15;68(20):8295-303. doi: 10.1158/0008-5472.CAN-07-6601. Cancer Res. 2008. PMID: 18922901 Free PMC article.

7

The Adnectin CT-322 is a novel VEGF receptor 2 inhibitor that decreases tumor burden in an orthotopic mouse model of pancreatic cancer.

Dineen SP, Sullivan LA, Beck AW, Miller AF, Carbon JG, Mamluk R, Wong H, Brekken RA. Dineen SP, et al. Among authors: brekken ra. BMC Cancer. 2008 Nov 27;8:352. doi: 10.1186/1471-2407-8-352. BMC Cancer. 2008. PMID: 19038046 Free PMC article.

8

Inhibition of vascular endothelial growth factor reduces angiogenesis and modulates immune cell infiltration of orthotopic breast cancer xenografts.

Roland CL, Dineen SP, Lynn KD, Sullivan LA, Dellinger MT, Sadegh L, Sullivan JP, Shames DS, Brekken RA. Roland CL, et al. Among authors: brekken ra. Mol Cancer Ther. 2009 Jul;8(7):1761-71. doi: 10.1158/1535-7163.MCT-09-0280. Epub 2009 Jun 30. Mol Cancer Ther. 2009. PMID: 19567820

9

Cytokine levels correlate with immune cell infiltration after anti-VEGF therapy in preclinical mouse models of breast cancer.

Roland CL, Lynn KD, Toombs JE, Dineen SP, Udugamasooriya DG, Brekken RA. Roland CL, et al. Among authors: brekken ra. PLoS One. 2009 Nov 3;4(11):e7669. doi: 10.1371/journal.pone.0007669. PLoS One. 2009. PMID: 19888452 Free PMC article.

10

The VEGF family in cancer and antibody-based strategies for their inhibition.

Sullivan LA, Brekken RA. Sullivan LA, et al. Among authors: brekken ra. MAbs. 2010 Mar-Apr;2(2):165-75. doi: 10.4161/mabs.2.2.11360. MAbs. 2010. PMID: 20190566 Free PMC article. Review.

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