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Aldosterone acutely stimulates NCC activity via a SPAK-mediated pathway.
Ko B, Mistry AC, Hanson L, Mallick R, Wynne BM, Thai TL, Bailey JL, Klein JD, Hoover RS. Ko B, et al. Among authors: wynne bm. Am J Physiol Renal Physiol. 2013 Sep 1;305(5):F645-52. doi: 10.1152/ajprenal.00053.2013. Epub 2013 Jun 5. Am J Physiol Renal Physiol. 2013. PMID: 23739593 Free PMC article.
Pendrin localizes to the adrenal medulla and modulates catecholamine release.
Lazo-Fernandez Y, Aguilera G, Pham TD, Park AY, Beierwaltes WH, Sutliff RL, Verlander JW, Pacak K, Osunkoya AO, Ellis CL, Kim YH, Shipley GL, Wynne BM, Hoover RS, Sen SK, Plotsky PM, Wall SM. Lazo-Fernandez Y, et al. Among authors: wynne bm. Am J Physiol Endocrinol Metab. 2015 Sep 15;309(6):E534-45. doi: 10.1152/ajpendo.00035.2015. Epub 2015 Jul 14. Am J Physiol Endocrinol Metab. 2015. PMID: 26173457 Free PMC article.
The sodium chloride cotransporter (NCC) and epithelial sodium channel (ENaC) associate.
Mistry AC, Wynne BM, Yu L, Tomilin V, Yue Q, Zhou Y, Al-Khalili O, Mallick R, Cai H, Alli AA, Ko B, Mattheyses A, Bao HF, Pochynyuk O, Theilig F, Eaton DC, Hoover RS. Mistry AC, et al. Among authors: wynne bm. Biochem J. 2016 Oct 1;473(19):3237-52. doi: 10.1042/BCJ20160312. Epub 2016 Jul 15. Biochem J. 2016. PMID: 27422782 Free PMC article.
Aldosterone Modulates the Association between NCC and ENaC.
Wynne BM, Mistry AC, Al-Khalili O, Mallick R, Theilig F, Eaton DC, Hoover RS. Wynne BM, et al. Sci Rep. 2017 Jun 23;7(1):4149. doi: 10.1038/s41598-017-03510-5. Sci Rep. 2017. PMID: 28646163 Free PMC article.
TNF-alpha knockout mice have increased corpora cavernosa relaxation.
Carneiro FS, Sturgis LC, Giachini FR, Carneiro ZN, Lima VV, Wynne BM, San Martin S, Brands MW, Tostes RC, Webb RC. Carneiro FS, et al. Among authors: wynne bm. J Sex Med. 2009 Jan;6(1):115-25. doi: 10.1111/j.1743-6109.2008.01029.x. J Sex Med. 2009. PMID: 19170842 Free PMC article.
302 results