Zhang L - Search Results

1

The CPVT-associated RyR2 mutation G230C enhances store overload-induced Ca2+ release and destabilizes the N-terminal domains.

Liu Y, Kimlicka L, Hiess F, Tian X, Wang R, Zhang L, Jones PP, Van Petegem F, Chen SR. Liu Y, et al. Among authors: zhang l. Biochem J. 2013 Aug 15;454(1):123-31. doi: 10.1042/BJ20130594. Biochem J. 2013. PMID: 23746327

2

RyR2 mutations linked to ventricular tachycardia and sudden death reduce the threshold for store-overload-induced Ca2+ release (SOICR).

Jiang D, Xiao B, Yang D, Wang R, Choi P, Zhang L, Cheng H, Chen SR. Jiang D, et al. Among authors: zhang l. Proc Natl Acad Sci U S A. 2004 Aug 31;101(35):13062-7. doi: 10.1073/pnas.0402388101. Epub 2004 Aug 20. Proc Natl Acad Sci U S A. 2004. PMID: 15322274 Free PMC article.

3

Enhanced store overload-induced Ca2+ release and channel sensitivity to luminal Ca2+ activation are common defects of RyR2 mutations linked to ventricular tachycardia and sudden death.

Jiang D, Wang R, Xiao B, Kong H, Hunt DJ, Choi P, Zhang L, Chen SR. Jiang D, et al. Among authors: zhang l. Circ Res. 2005 Nov 25;97(11):1173-81. doi: 10.1161/01.RES.0000192146.85173.4b. Epub 2005 Oct 20. Circ Res. 2005. PMID: 16239587

4

Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+.

Kong H, Wang R, Chen W, Zhang L, Chen K, Shimoni Y, Duff HJ, Chen SR. Kong H, et al. Among authors: zhang l. Biophys J. 2007 Apr 15;92(8):2757-70. doi: 10.1529/biophysj.106.100545. Epub 2007 Jan 26. Biophys J. 2007. PMID: 17259277 Free PMC article.

5

Functional consequence of protein kinase A-dependent phosphorylation of the cardiac ryanodine receptor: sensitization of store overload-induced Ca2+ release.

Xiao B, Tian X, Xie W, Jones PP, Cai S, Wang X, Jiang D, Kong H, Zhang L, Chen K, Walsh MP, Cheng H, Chen SR. Xiao B, et al. Among authors: zhang l. J Biol Chem. 2007 Oct 12;282(41):30256-64. doi: 10.1074/jbc.M703510200. Epub 2007 Aug 10. J Biol Chem. 2007. PMID: 17693412 Free article.

6

Removal of FKBP12.6 does not alter the conductance and activation of the cardiac ryanodine receptor or the susceptibility to stress-induced ventricular arrhythmias.

Xiao J, Tian X, Jones PP, Bolstad J, Kong H, Wang R, Zhang L, Duff HJ, Gillis AM, Fleischer S, Kotlikoff M, Copello JA, Chen SR. Xiao J, et al. Among authors: zhang l. J Biol Chem. 2007 Nov 30;282(48):34828-38. doi: 10.1074/jbc.M707423200. Epub 2007 Oct 5. J Biol Chem. 2007. PMID: 17921453 Free PMC article.

7

Loss of luminal Ca2+ activation in the cardiac ryanodine receptor is associated with ventricular fibrillation and sudden death.

Jiang D, Chen W, Wang R, Zhang L, Chen SR. Jiang D, et al. Among authors: zhang l. Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):18309-14. doi: 10.1073/pnas.0706573104. Epub 2007 Nov 1. Proc Natl Acad Sci U S A. 2007. PMID: 17984046 Free PMC article.

8

Endoplasmic reticulum Ca2+ measurements reveal that the cardiac ryanodine receptor mutations linked to cardiac arrhythmia and sudden death alter the threshold for store-overload-induced Ca2+ release.

Jones PP, Jiang D, Bolstad J, Hunt DJ, Zhang L, Demaurex N, Chen SR. Jones PP, et al. Among authors: zhang l. Biochem J. 2008 May 15;412(1):171-8. doi: 10.1042/BJ20071287. Biochem J. 2008. PMID: 18092949

9

Caffeine induces Ca2+ release by reducing the threshold for luminal Ca2+ activation of the ryanodine receptor.

Kong H, Jones PP, Koop A, Zhang L, Duff HJ, Chen SR. Kong H, et al. Among authors: zhang l. Biochem J. 2008 Sep 15;414(3):441-52. doi: 10.1042/BJ20080489. Biochem J. 2008. PMID: 18518861 Free PMC article.

10

Carvedilol and its new analogs suppress arrhythmogenic store overload-induced Ca2+ release.

Zhou Q, Xiao J, Jiang D, Wang R, Vembaiyan K, Wang A, Smith CD, Xie C, Chen W, Zhang J, Tian X, Jones PP, Zhong X, Guo A, Chen H, Zhang L, Zhu W, Yang D, Li X, Chen J, Gillis AM, Duff HJ, Cheng H, Feldman AM, Song LS, Fill M, Back TG, Chen SR. Zhou Q, et al. Among authors: zhang l, zhang j. Nat Med. 2011 Jul 10;17(8):1003-9. doi: 10.1038/nm.2406. Nat Med. 2011. PMID: 21743453 Free PMC article.

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