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1,276 results

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Gastrointestinal pain: unraveling a novel endogenous pathway through uroguanylin/guanylate cyclase-C/cGMP activation.
Silos-Santiago I, Hannig G, Eutamene H, Ustinova EE, Bernier SG, Ge P, Graul C, Jacobson S, Jin H, Liong E, Kessler MM, Reza T, Rivers S, Shea C, Tchernychev B, Bryant AP, Kurtz CB, Bueno L, Pezzone MA, Currie MG. Silos-Santiago I, et al. Among authors: ge p. Pain. 2013 Sep;154(9):1820-1830. doi: 10.1016/j.pain.2013.05.044. Epub 2013 Jun 5. Pain. 2013. PMID: 23748116 Free article.
MRP4 Modulation of the Guanylate Cyclase-C/cGMP Pathway: Effects on Linaclotide-Induced Electrolyte Secretion and cGMP Efflux.
Tchernychev B, Ge P, Kessler MM, Solinga RM, Wachtel D, Tobin JV, Thomas SR, Lunte CE, Fretzen A, Hannig G, Bryant AP, Kurtz CB, Currie MG, Silos-Santiago I. Tchernychev B, et al. Among authors: ge p. J Pharmacol Exp Ther. 2015 Oct;355(1):48-56. doi: 10.1124/jpet.115.224329. Epub 2015 Jul 27. J Pharmacol Exp Ther. 2015. PMID: 26216942
Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3',5'-monophosphate.
Castro J, Harrington AM, Hughes PA, Martin CM, Ge P, Shea CM, Jin H, Jacobson S, Hannig G, Mann E, Cohen MB, MacDougall JE, Lavins BJ, Kurtz CB, Silos-Santiago I, Johnston JM, Currie MG, Blackshaw LA, Brierley SM. Castro J, et al. Among authors: ge p. Gastroenterology. 2013 Dec;145(6):1334-46.e1-11. doi: 10.1053/j.gastro.2013.08.017. Epub 2013 Aug 16. Gastroenterology. 2013. PMID: 23958540 Free article. Clinical Trial.
Chronic linaclotide treatment reduces colitis-induced neuroplasticity and reverses persistent bladder dysfunction.
Grundy L, Harrington AM, Castro J, Garcia-Caraballo S, Deiteren A, Maddern J, Rychkov GY, Ge P, Peters S, Feil R, Miller P, Ghetti A, Hannig G, Kurtz CB, Silos-Santiago I, Brierley SM. Grundy L, et al. Among authors: ge p. JCI Insight. 2018 Oct 4;3(19):e121841. doi: 10.1172/jci.insight.121841. JCI Insight. 2018. PMID: 30282832 Free PMC article.
Intestinal Guanylate Cyclase-C mRNA Expression in Duodenum and Colon of Children.
Cohen MB, Gold BD, Xanthakos SA, CaJacob N, Weissman T, Bartolini W, Boinpally R, Mallick M, Reasner DS, O'Dea CR, Kwak H, Ge P. Cohen MB, et al. Among authors: ge p. J Pediatr Gastroenterol Nutr. 2021 Dec 1;73(6):703-709. doi: 10.1097/MPG.0000000000003296. J Pediatr Gastroenterol Nutr. 2021. PMID: 34508047
1,276 results