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Hepatic activation of irinotecan predicts tumour response in patients with colorectal liver metastases treated with DEBIRI: exploratory findings from a phase II study.
Jones RP, Sutton P, Greensmith RM, Santoyo-Castelazo A, Carr DF, Jenkins R, Rowe C, Hamlett J, Park BK, Terlizzo M, O'Grady E, Ghaneh P, Fenwick SW, Malik HZ, Poston GJ, Kitteringham NR. Jones RP, et al. Among authors: rowe c. Cancer Chemother Pharmacol. 2013 Aug;72(2):359-68. doi: 10.1007/s00280-013-2199-5. Epub 2013 Jun 12. Cancer Chemother Pharmacol. 2013. PMID: 23756919 Clinical Trial.
Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile.
Heslop JA, Rowe C, Walsh J, Sison-Young R, Jenkins R, Kamalian L, Kia R, Hay D, Jones RP, Malik HZ, Fenwick S, Chadwick AE, Mills J, Kitteringham NR, Goldring CE, Kevin Park B. Heslop JA, et al. Among authors: rowe c. Arch Toxicol. 2017 Jan;91(1):439-452. doi: 10.1007/s00204-016-1694-y. Epub 2016 Apr 2. Arch Toxicol. 2017. PMID: 27039104 Free PMC article.
Human pluripotent stem cells for modeling toxicity.
Sison-Young RL, Kia R, Heslop J, Kelly L, Rowe C, Cross MJ, Kitteringham NR, Hanley N, Park BK, Goldring CE. Sison-Young RL, et al. Among authors: rowe c. Adv Pharmacol. 2012;63:207-56. doi: 10.1016/B978-0-12-398339-8.00006-9. Adv Pharmacol. 2012. PMID: 22776643 Review.
Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes.
Baxter M, Withey S, Harrison S, Segeritz CP, Zhang F, Atkinson-Dell R, Rowe C, Gerrard DT, Sison-Young R, Jenkins R, Henry J, Berry AA, Mohamet L, Best M, Fenwick SW, Malik H, Kitteringham NR, Goldring CE, Piper Hanley K, Vallier L, Hanley NA. Baxter M, et al. Among authors: rowe c. J Hepatol. 2015 Mar;62(3):581-9. doi: 10.1016/j.jhep.2014.10.016. Epub 2014 Oct 18. J Hepatol. 2015. PMID: 25457200 Free PMC article.
Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney.
Shelton LM, Lister A, Walsh J, Jenkins RE, Wong MH, Rowe C, Ricci E, Ressel L, Fang Y, Demougin P, Vukojevic V, O'Neill PM, Goldring CE, Kitteringham NR, Park BK, Odermatt A, Copple IM. Shelton LM, et al. Among authors: rowe c. Kidney Int. 2015 Dec;88(6):1261-1273. doi: 10.1038/ki.2015.286. Epub 2015 Sep 30. Kidney Int. 2015. PMID: 26422507 Free PMC article.
1,120 results