Kelleher NL - Search Results

1

Proteomics guided discovery of flavopeptins: anti-proliferative aldehydes synthesized by a reductase domain-containing non-ribosomal peptide synthetase.

Chen Y, McClure RA, Zheng Y, Thomson RJ, Kelleher NL. Chen Y, et al. Among authors: kelleher nl. J Am Chem Soc. 2013 Jul 17;135(28):10449-56. doi: 10.1021/ja4031193. Epub 2013 Jul 2. J Am Chem Soc. 2013. PMID: 23763305 Free PMC article.

2

Kinetic and regiospecific interrogation of covalent intermediates in the nonribosomal peptide synthesis of yersiniabactin.

McLoughlin SM, Kelleher NL. McLoughlin SM, et al. Among authors: kelleher nl. J Am Chem Soc. 2004 Oct 20;126(41):13265-75. doi: 10.1021/ja0470867. J Am Chem Soc. 2004. PMID: 15479080 Free PMC article.

3

Lacticin 481 synthetase phosphorylates its substrate during lantibiotic production.

Chatterjee C, Miller LM, Leung YL, Xie L, Yi M, Kelleher NL, van der Donk WA. Chatterjee C, et al. Among authors: kelleher nl. J Am Chem Soc. 2005 Nov 9;127(44):15332-3. doi: 10.1021/ja0543043. J Am Chem Soc. 2005. PMID: 16262372

4

The dehydratase activity of lacticin 481 synthetase is highly processive.

Miller LM, Chatterjee C, van der Donk WA, Kelleher NL. Miller LM, et al. Among authors: kelleher nl. J Am Chem Soc. 2006 Feb 8;128(5):1420-1. doi: 10.1021/ja057203d. J Am Chem Soc. 2006. PMID: 16448091 Free PMC article.

5

Polyunsaturated fatty-acid-like trans-enoyl reductases utilized in polyketide biosynthesis.

Bumpus SB, Magarvey NA, Kelleher NL, Walsh CT, Calderone CT. Bumpus SB, et al. Among authors: kelleher nl. J Am Chem Soc. 2008 Sep 3;130(35):11614-6. doi: 10.1021/ja8040042. Epub 2008 Aug 12. J Am Chem Soc. 2008. PMID: 18693732 Free PMC article.

6

The nonribosomal peptide synthetase enzyme DdaD tethers N(β)-fumaramoyl-l-2,3-diaminopropionate for Fe(II)/α-ketoglutarate-dependent epoxidation by DdaC during dapdiamide antibiotic biosynthesis.

Hollenhorst MA, Bumpus SB, Matthews ML, Bollinger JM Jr, Kelleher NL, Walsh CT. Hollenhorst MA, et al. Among authors: kelleher nl. J Am Chem Soc. 2010 Nov 10;132(44):15773-81. doi: 10.1021/ja1072367. J Am Chem Soc. 2010. PMID: 20945916 Free PMC article.

7

Proteomics-based discovery of koranimine, a cyclic imine natural product.

Evans BS, Ntai I, Chen Y, Robinson SJ, Kelleher NL. Evans BS, et al. Among authors: kelleher nl. J Am Chem Soc. 2011 May 18;133(19):7316-9. doi: 10.1021/ja2015795. Epub 2011 Apr 26. J Am Chem Soc. 2011. PMID: 21520944 Free PMC article.

8

Directed evolution of the nonribosomal peptide synthetase AdmK generates new andrimid derivatives in vivo.

Evans BS, Chen Y, Metcalf WW, Zhao H, Kelleher NL. Evans BS, et al. Among authors: kelleher nl. Chem Biol. 2011 May 27;18(5):601-7. doi: 10.1016/j.chembiol.2011.03.008. Chem Biol. 2011. PMID: 21609841 Free PMC article.

9

A proteomic survey of nonribosomal peptide and polyketide biosynthesis in actinobacteria.

Chen Y, Ntai I, Ju KS, Unger M, Zamdborg L, Robinson SJ, Doroghazi JR, Labeda DP, Metcalf WW, Kelleher NL. Chen Y, et al. Among authors: kelleher nl. J Proteome Res. 2012 Jan 1;11(1):85-94. doi: 10.1021/pr2009115. Epub 2011 Oct 25. J Proteome Res. 2012. PMID: 21978092 Free PMC article.

10

Ion mobility separation of variant histone tails extending to the "middle-down" range.

Shvartsburg AA, Zheng Y, Smith RD, Kelleher NL. Shvartsburg AA, et al. Among authors: kelleher nl. Anal Chem. 2012 May 15;84(10):4271-6. doi: 10.1021/ac300612y. Epub 2012 May 3. Anal Chem. 2012. PMID: 22559289 Free PMC article.

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