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Whole-body scanning PCR; a highly sensitive method to study the biodistribution of mRNAs, noncoding RNAs and therapeutic oligonucleotides.
Boos JA, Kirk DW, Piccolotto ML, Zuercher W, Gfeller S, Neuner P, Dattler A, Wishart WL, Von Arx F, Beverly M, Christensen J, Litherland K, van de Kerkhof E, Swart PJ, Faller T, Beyerbach A, Morrissey D, Hunziker J, Beuvink I. Boos JA, et al. Among authors: faller t. Nucleic Acids Res. 2013 Aug;41(15):e145. doi: 10.1093/nar/gkt515. Epub 2013 Jun 13. Nucleic Acids Res. 2013. PMID: 23766292 Free PMC article.
Biodistribution and metabolism studies of lipid nanoparticle-formulated internally [3H]-labeled siRNA in mice.
Christensen J, Litherland K, Faller T, van de Kerkhof E, Natt F, Hunziker J, Boos J, Beuvink I, Bowman K, Baryza J, Beverly M, Vargeese C, Heudi O, Stoeckli M, Krauser J, Swart P. Christensen J, et al. Among authors: faller t. Drug Metab Dispos. 2014 Mar;42(3):431-40. doi: 10.1124/dmd.113.055434. Epub 2014 Jan 3. Drug Metab Dispos. 2014. PMID: 24389421
NVP-QBE170: an inhaled blocker of the epithelial sodium channel with a reduced potential to induce hyperkalaemia.
Coote KJ, Paisley D, Czarnecki S, Tweed M, Watson H, Young A, Sugar R, Vyas M, Smith NJ, Baettig U, Groot-Kormelink PJ, Gosling M, Lock R, Ethell B, Williams G, Schumacher A, Harris J, Abraham WM, Sabater J, Poll CT, Faller T, Collingwood SP, Danahay H. Coote KJ, et al. Among authors: faller t. Br J Pharmacol. 2015 Jun;172(11):2814-26. doi: 10.1111/bph.13075. Epub 2015 Apr 23. Br J Pharmacol. 2015. PMID: 25573195 Free PMC article.
Propylene oxide in blood and soluble nonprotein thiols in nasal mucosa and other tissues of male Fischer 344/N rats exposed to propylene oxide vapors--relevance of glutathione depletion for propylene oxide-induced rat nasal tumors.
Lee MS, Faller TH, Kreuzer PE, Kessler W, Csanády GA, Pütz C, Ríos-Blanco MN, Pottenger LH, Segerbäck D, Osterman-Golkar S, Swenberg JA, Filser JG. Lee MS, et al. Toxicol Sci. 2005 Jan;83(1):177-89. doi: 10.1093/toxsci/kfi006. Epub 2004 Oct 13. Toxicol Sci. 2005. PMID: 15483188
61 results