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Page 1
Antituberculosis thiophenes define a requirement for Pks13 in mycolic acid biosynthesis.
Wilson R, Kumar P, Parashar V, Vilchèze C, Veyron-Churlet R, Freundlich JS, Barnes SW, Walker JR, Szymonifka MJ, Marchiano E, Shenai S, Colangeli R, Jacobs WR Jr, Neiditch MB, Kremer L, Alland D. Wilson R, et al. Among authors: shenai s. Nat Chem Biol. 2013 Aug;9(8):499-506. doi: 10.1038/nchembio.1277. Epub 2013 Jun 16. Nat Chem Biol. 2013. PMID: 23770708 Free PMC article.
Phosphorylation of KasB regulates virulence and acid-fastness in Mycobacterium tuberculosis.
Vilchèze C, Molle V, Carrère-Kremer S, Leiba J, Mourey L, Shenai S, Baronian G, Tufariello J, Hartman T, Veyron-Churlet R, Trivelli X, Tiwari S, Weinrick B, Alland D, Guérardel Y, Jacobs WR Jr, Kremer L. Vilchèze C, et al. Among authors: shenai s. PLoS Pathog. 2014 May 8;10(5):e1004115. doi: 10.1371/journal.ppat.1004115. eCollection 2014 May. PLoS Pathog. 2014. PMID: 24809459 Free PMC article.
Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure.
Malherbe ST, Shenai S, Ronacher K, Loxton AG, Dolganov G, Kriel M, Van T, Chen RY, Warwick J, Via LE, Song T, Lee M, Schoolnik G, Tromp G, Alland D, Barry CE 3rd, Winter J, Walzl G; Catalysis TB–Biomarker Consortium; Lucas L, Spuy GV, Stanley K, Thiart L, Smith B, Du Plessis N, Beltran CG, Maasdorp E, Ellmann A, Choi H, Joh J, Dodd LE, Allwood B, Koegelenberg C, Vorster M, Griffith-Richards S. Malherbe ST, et al. Among authors: shenai s. Nat Med. 2016 Oct;22(10):1094-1100. doi: 10.1038/nm.4177. Epub 2016 Sep 5. Nat Med. 2016. PMID: 27595324 Free PMC article.
Detection of Isoniazid-, Fluoroquinolone-, Amikacin-, and Kanamycin-Resistant Tuberculosis in an Automated, Multiplexed 10-Color Assay Suitable for Point-of-Care Use.
Chakravorty S, Roh SS, Glass J, Smith LE, Simmons AM, Lund K, Lokhov S, Liu X, Xu P, Zhang G, Via LE, Shen Q, Ruan X, Yuan X, Zhu HZ, Viazovkina E, Shenai S, Rowneki M, Lee JS, Barry CE 3rd, Gao Q, Persing D, Kwiatkawoski R, Jones M, Gall A, Alland D. Chakravorty S, et al. Among authors: shenai s. J Clin Microbiol. 2016 Dec 28;55(1):183-198. doi: 10.1128/JCM.01771-16. Print 2017 Jan. J Clin Microbiol. 2016. PMID: 27807153 Free PMC article.
The New Xpert MTB/RIF Ultra: Improving Detection of Mycobacterium tuberculosis and Resistance to Rifampin in an Assay Suitable for Point-of-Care Testing.
Chakravorty S, Simmons AM, Rowneki M, Parmar H, Cao Y, Ryan J, Banada PP, Deshpande S, Shenai S, Gall A, Glass J, Krieswirth B, Schumacher SG, Nabeta P, Tukvadze N, Rodrigues C, Skrahina A, Tagliani E, Cirillo DM, Davidow A, Denkinger CM, Persing D, Kwiatkowski R, Jones M, Alland D. Chakravorty S, et al. Among authors: shenai s. mBio. 2017 Aug 29;8(4):e00812-17. doi: 10.1128/mBio.00812-17. mBio. 2017. PMID: 28851844 Free PMC article.
Host blood RNA signatures predict the outcome of tuberculosis treatment.
Thompson EG, Du Y, Malherbe ST, Shankar S, Braun J, Valvo J, Ronacher K, Tromp G, Tabb DL, Alland D, Shenai S, Via LE, Warwick J, Aderem A, Scriba TJ, Winter J, Walzl G, Zak DE; Catalysis TB–Biomarker Consortium. Thompson EG, et al. Among authors: shenai s. Tuberculosis (Edinb). 2017 Dec;107:48-58. doi: 10.1016/j.tube.2017.08.004. Epub 2017 Aug 12. Tuberculosis (Edinb). 2017. PMID: 29050771 Free PMC article.
Analytical and Clinical Evaluation of the Epistem Genedrive Assay for Detection of Mycobacterium tuberculosis.
Shenai S, Armstrong DT, Valli E, Dolinger DL, Nakiyingi L, Dietze R, Dalcolmo MP, Nicol MP, Zemanay W, Manabe Y, Hadad DJ, Marques-Rodrigues P, Palaci M, Peres RL, Gaeddert M, Armakovitch S, Nonyane BA, Denkinger CM, Banada P, Joloba ML, Ellner J, Boehme C, Alland D, Dorman SE. Shenai S, et al. J Clin Microbiol. 2016 Apr;54(4):1051-7. doi: 10.1128/JCM.02847-15. Epub 2016 Feb 10. J Clin Microbiol. 2016. PMID: 26865685 Free PMC article.
Rapid molecular detection of tuberculosis and rifampin resistance.
Boehme CC, Nabeta P, Hillemann D, Nicol MP, Shenai S, Krapp F, Allen J, Tahirli R, Blakemore R, Rustomjee R, Milovic A, Jones M, O'Brien SM, Persing DH, Ruesch-Gerdes S, Gotuzzo E, Rodrigues C, Alland D, Perkins MD. Boehme CC, et al. Among authors: shenai s. N Engl J Med. 2010 Sep 9;363(11):1005-15. doi: 10.1056/NEJMoa0907847. Epub 2010 Sep 1. N Engl J Med. 2010. PMID: 20825313 Free PMC article. Clinical Trial.
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