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Page 1
Microbial translocation is a cause of systemic immune activation in chronic HIV infection.
Brenchley JM, Price DA, Schacker TW, Asher TE, Silvestri G, Rao S, Kazzaz Z, Bornstein E, Lambotte O, Altmann D, Blazar BR, Rodriguez B, Teixeira-Johnson L, Landay A, Martin JN, Hecht FM, Picker LJ, Lederman MM, Deeks SG, Douek DC. Brenchley JM, et al. Among authors: douek dc. Nat Med. 2006 Dec;12(12):1365-71. doi: 10.1038/nm1511. Epub 2006 Nov 19. Nat Med. 2006. PMID: 17115046
Severe depletion of mucosal CD4+ T cells in AIDS-free simian immunodeficiency virus-infected sooty mangabeys.
Gordon SN, Klatt NR, Bosinger SE, Brenchley JM, Milush JM, Engram JC, Dunham RM, Paiardini M, Klucking S, Danesh A, Strobert EA, Apetrei C, Pandrea IV, Kelvin D, Douek DC, Staprans SI, Sodora DL, Silvestri G. Gordon SN, et al. Among authors: douek dc. J Immunol. 2007 Sep 1;179(5):3026-34. doi: 10.4049/jimmunol.179.5.3026. J Immunol. 2007. PMID: 17709517 Free PMC article.
Plasma levels of bacterial DNA correlate with immune activation and the magnitude of immune restoration in persons with antiretroviral-treated HIV infection.
Jiang W, Lederman MM, Hunt P, Sieg SF, Haley K, Rodriguez B, Landay A, Martin J, Sinclair E, Asher AI, Deeks SG, Douek DC, Brenchley JM. Jiang W, et al. Among authors: douek dc. J Infect Dis. 2009 Apr 15;199(8):1177-85. doi: 10.1086/597476. J Infect Dis. 2009. PMID: 19265479 Free PMC article. Clinical Trial.
HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation.
Chomont N, El-Far M, Ancuta P, Trautmann L, Procopio FA, Yassine-Diab B, Boucher G, Boulassel MR, Ghattas G, Brenchley JM, Schacker TW, Hill BJ, Douek DC, Routy JP, Haddad EK, Sékaly RP. Chomont N, et al. Among authors: douek dc. Nat Med. 2009 Aug;15(8):893-900. doi: 10.1038/nm.1972. Epub 2009 Jun 21. Nat Med. 2009. PMID: 19543283 Free PMC article. Clinical Trial.
Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques.
Harris LD, Tabb B, Sodora DL, Paiardini M, Klatt NR, Douek DC, Silvestri G, Müller-Trutwin M, Vasile-Pandrea I, Apetrei C, Hirsch V, Lifson J, Brenchley JM, Estes JD. Harris LD, et al. Among authors: douek dc. J Virol. 2010 Aug;84(15):7886-91. doi: 10.1128/JVI.02612-09. Epub 2010 May 19. J Virol. 2010. PMID: 20484518 Free PMC article.
Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease.
Favre D, Mold J, Hunt PW, Kanwar B, Loke P, Seu L, Barbour JD, Lowe MM, Jayawardene A, Aweeka F, Huang Y, Douek DC, Brenchley JM, Martin JN, Hecht FM, Deeks SG, McCune JM. Favre D, et al. Among authors: douek dc. Sci Transl Med. 2010 May 19;2(32):32ra36. doi: 10.1126/scitranslmed.3000632. Sci Transl Med. 2010. PMID: 20484731 Free PMC article.
457 results