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Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss.
Talantova M, Sanz-Blasco S, Zhang X, Xia P, Akhtar MW, Okamoto S, Dziewczapolski G, Nakamura T, Cao G, Pratt AE, Kang YJ, Tu S, Molokanova E, McKercher SR, Hires SA, Sason H, Stouffer DG, Buczynski MW, Solomon JP, Michael S, Powers ET, Kelly JW, Roberts A, Tong G, Fang-Newmeyer T, Parker J, Holland EA, Zhang D, Nakanishi N, Chen HS, Wolosker H, Wang Y, Parsons LH, Ambasudhan R, Masliah E, Heinemann SF, Piña-Crespo JC, Lipton SA. Talantova M, et al. Among authors: buczynski mw. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):E2518-27. doi: 10.1073/pnas.1306832110. Epub 2013 Jun 17. Proc Natl Acad Sci U S A. 2013. PMID: 23776240 Free PMC article.
Diacylglycerol lipase disinhibits VTA dopamine neurons during chronic nicotine exposure.
Buczynski MW, Herman MA, Hsu KL, Natividad LA, Irimia C, Polis IY, Pugh H, Chang JW, Niphakis MJ, Cravatt BF, Roberto M, Parsons LH. Buczynski MW, et al. Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):1086-91. doi: 10.1073/pnas.1522672113. Epub 2016 Jan 11. Proc Natl Acad Sci U S A. 2016. PMID: 26755579 Free PMC article.
Deficient endocannabinoid signaling in the central amygdala contributes to alcohol dependence-related anxiety-like behavior and excessive alcohol intake.
Serrano A, Pavon FJ, Buczynski MW, Schlosburg J, Natividad LA, Polis IY, Stouffer DG, Zorrilla EP, Roberto M, Cravatt BF, Martin-Fardon R, Rodriguez de Fonseca F, Parsons LH. Serrano A, et al. Among authors: buczynski mw. Neuropsychopharmacology. 2018 Aug;43(9):1840-1850. doi: 10.1038/s41386-018-0055-3. Epub 2018 Apr 5. Neuropsychopharmacology. 2018. PMID: 29748627 Free PMC article.
Phosphorylation of calcium/calmodulin-dependent protein kinase II in the rat dorsal medial prefrontal cortex is associated with alcohol-induced cognitive inflexibility.
Natividad LA, Steinman MQ, Laredo SA, Irimia C, Polis IY, Lintz R, Buczynski MW, Martin-Fardon R, Roberto M, Parsons LH. Natividad LA, et al. Among authors: buczynski mw. Addict Biol. 2018 Sep;23(5):1117-1129. doi: 10.1111/adb.12568. Epub 2017 Sep 22. Addict Biol. 2018. PMID: 28940879 Free PMC article.
43 results