Mortimer SA - Search Results

1

SHAPE-Seq: High-Throughput RNA Structure Analysis.

Mortimer SA, Trapnell C, Aviran S, Pachter L, Lucks JB. Mortimer SA, et al. Curr Protoc Chem Biol. 2012 Dec 1;4(4):275-97. doi: 10.1002/9780470559277.ch120019. Curr Protoc Chem Biol. 2012. PMID: 23788555

2

Multiplexed RNA structure characterization with selective 2'-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq).

Lucks JB, Mortimer SA, Trapnell C, Luo S, Aviran S, Schroth GP, Pachter L, Doudna JA, Arkin AP. Lucks JB, et al. Among authors: mortimer sa. Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11063-8. doi: 10.1073/pnas.1106501108. Epub 2011 Jun 3. Proc Natl Acad Sci U S A. 2011. PMID: 21642531 Free PMC article.

3

Modeling and automation of sequencing-based characterization of RNA structure.

Aviran S, Trapnell C, Lucks JB, Mortimer SA, Luo S, Schroth GP, Doudna JA, Arkin AP, Pachter L. Aviran S, et al. Among authors: mortimer sa. Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11069-74. doi: 10.1073/pnas.1106541108. Epub 2011 Jun 3. Proc Natl Acad Sci U S A. 2011. PMID: 21642536 Free PMC article.

4

Insights into RNA structure and function from genome-wide studies.

Mortimer SA, Kidwell MA, Doudna JA. Mortimer SA, et al. Nat Rev Genet. 2014 Jul;15(7):469-79. doi: 10.1038/nrg3681. Epub 2014 May 13. Nat Rev Genet. 2014. PMID: 24821474 Review.

5

Unconventional miR-122 binding stabilizes the HCV genome by forming a trimolecular RNA structure.

Mortimer SA, Doudna JA. Mortimer SA, et al. Nucleic Acids Res. 2013 Apr;41(7):4230-40. doi: 10.1093/nar/gkt075. Epub 2013 Feb 14. Nucleic Acids Res. 2013. PMID: 23416544 Free PMC article.

6

Time-resolved RNA SHAPE chemistry: quantitative RNA structure analysis in one-second snapshots and at single-nucleotide resolution.

Mortimer SA, Weeks KM. Mortimer SA, et al. Nat Protoc. 2009;4(10):1413-21. doi: 10.1038/nprot.2009.126. Epub 2009 Sep 10. Nat Protoc. 2009. PMID: 19745823 Free PMC article.

7

Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation.

Sun C, Querol-Audí J, Mortimer SA, Arias-Palomo E, Doudna JA, Nogales E, Cate JH. Sun C, et al. Among authors: mortimer sa. Nucleic Acids Res. 2013 Aug;41(15):7512-21. doi: 10.1093/nar/gkt510. Epub 2013 Jun 13. Nucleic Acids Res. 2013. PMID: 23766293 Free PMC article.

8

Time-resolved RNA SHAPE chemistry.

Mortimer SA, Weeks KM. Mortimer SA, et al. J Am Chem Soc. 2008 Dec 3;130(48):16178-80. doi: 10.1021/ja8061216. J Am Chem Soc. 2008. PMID: 18998638

9

Crystal structure of the HCV IRES central domain reveals strategy for start-codon positioning.

Berry KE, Waghray S, Mortimer SA, Bai Y, Doudna JA. Berry KE, et al. Among authors: mortimer sa. Structure. 2011 Oct 12;19(10):1456-66. doi: 10.1016/j.str.2011.08.002. Structure. 2011. PMID: 22000514 Free PMC article.

10

Enhancement of hepatitis C viral RNA abundance by precursor miR-122 molecules.

Cox EM, Sagan SM, Mortimer SA, Doudna JA, Sarnow P. Cox EM, et al. Among authors: mortimer sa. RNA. 2013 Dec;19(12):1825-32. doi: 10.1261/rna.040865.113. Epub 2013 Oct 8. RNA. 2013. PMID: 24106328 Free PMC article.

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