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Page 1
A mucus production programme promotes classical pancreatic ductal adenocarcinoma.
Tonelli C, Yordanov GN, Hao Y, Deschênes A, Hinds J, Belleau P, Klingbeil O, Brosnan E, Doshi A, Park Y, Hruban RH, Vakoc CR, Dobin A, Preall J, Tuveson DA. Tonelli C, et al. Among authors: vakoc cr. Gut. 2024 May 10;73(6):941-954. doi: 10.1136/gutjnl-2023-329839. Gut. 2024. PMID: 38262672 Free PMC article.
Engrailed-1 Promotes Pancreatic Cancer Metastasis.
Xu J, Roe JS, Lee E, Tonelli C, Ji KY, Younis OW, Somervile TDD, Yao M, Milazzo JP, Tiriac H, Kolarzyk AM, Lee E, Grem JL, Lazenby AJ, Grunkemeyer JA, Hollingsworth MA, Grandgenett PM, Borowsky AD, Park Y, Vakoc CR, Tuveson DA, Hwang CI. Xu J, et al. Among authors: vakoc cr. Adv Sci (Weinh). 2024 Feb;11(6):e2308537. doi: 10.1002/advs.202308537. Epub 2023 Dec 18. Adv Sci (Weinh). 2024. PMID: 38110836 Free PMC article.
Marker-based CRISPR screening reveals a MED12-p63 interaction that activates basal identity in pancreatic ductal adenocarcinoma.
Maia-Silva D, Schier AC, Skopelitis D, Kechejian V, Alpsoy A, Liverpool J, Taatjes DJ, Vakoc CR. Maia-Silva D, et al. Among authors: vakoc cr. bioRxiv [Preprint]. 2023 Oct 27:2023.10.24.563848. doi: 10.1101/2023.10.24.563848. bioRxiv. 2023. Update in: Nat Genet. 2024 Jul;56(7):1377-1385. doi: 10.1038/s41588-024-01790-y. PMID: 37961243 Free PMC article. Updated. Preprint.
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.
Zuber J, Shi J, Wang E, Rappaport AR, Herrmann H, Sison EA, Magoon D, Qi J, Blatt K, Wunderlich M, Taylor MJ, Johns C, Chicas A, Mulloy JC, Kogan SC, Brown P, Valent P, Bradner JE, Lowe SW, Vakoc CR. Zuber J, et al. Among authors: vakoc cr. Nature. 2011 Aug 3;478(7370):524-8. doi: 10.1038/nature10334. Nature. 2011. PMID: 21814200 Free PMC article.
An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance.
Zuber J, Rappaport AR, Luo W, Wang E, Chen C, Vaseva AV, Shi J, Weissmueller S, Fellmann C, Taylor MJ, Weissenboeck M, Graeber TG, Kogan SC, Vakoc CR, Lowe SW. Zuber J, et al. Among authors: vakoc cr. Genes Dev. 2011 Aug 1;25(15):1628-40. doi: 10.1101/gad.17269211. Genes Dev. 2011. PMID: 21828272 Free PMC article.
BET bromodomain inhibition as a therapeutic strategy to target c-Myc.
Delmore JE, Issa GC, Lemieux ME, Rahl PB, Shi J, Jacobs HM, Kastritis E, Gilpatrick T, Paranal RM, Qi J, Chesi M, Schinzel AC, McKeown MR, Heffernan TP, Vakoc CR, Bergsagel PL, Ghobrial IM, Richardson PG, Young RA, Hahn WC, Anderson KC, Kung AL, Bradner JE, Mitsiades CS. Delmore JE, et al. Among authors: vakoc cr. Cell. 2011 Sep 16;146(6):904-17. doi: 10.1016/j.cell.2011.08.017. Epub 2011 Sep 1. Cell. 2011. PMID: 21889194 Free PMC article.
138 results