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Genome-wide case-only analysis of gene-gene interactions with known Parkinson's disease risk variants reveals link between LRRK2 and SYT10.
Aleknonytė-Resch M, Trinh J, Leonard H, Delcambre S, Leitão E, Lai D, Smajić S, Orr-Urtreger A, Thaler A, Blauwendraat C, Sharma A, Makarious MB, Kim JJ, Lake J, Rahmati P, Freitag-Wolf S, Seibler P, Foroud T, Singleton AB; International Parkinson Disease Genomics Consortium; Grünewald A, Kaiser F, Klein C, Krawczak M, Dempfle A. Aleknonytė-Resch M, et al. Among authors: grunewald a. NPJ Parkinsons Dis. 2023 Jun 29;9(1):102. doi: 10.1038/s41531-023-00550-9. NPJ Parkinsons Dis. 2023. PMID: 37386035 Free PMC article.
Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson's disease patients carrying the heterozygous mutations c.1290A > G (p.T351A) or c.2067A > G (p.T610A) in the RHOT1 gene encoding Miro1.
Chemla A, Arena G, Saraiva C, Berenguer-Escuder C, Grossmann D, Grünewald A, Klein C, Seibler P, Schwamborn JC, Krüger R. Chemla A, et al. Among authors: grunewald a. Stem Cell Res. 2023 Jun;69:103085. doi: 10.1016/j.scr.2023.103085. Epub 2023 Mar 25. Stem Cell Res. 2023. PMID: 37003181 Free PMC article.
Acylated and unacylated ghrelin confer neuroprotection to mesencephalic neurons.
Wagner J, Vulinović F, Grünewald A, Unger MM, Möller JC, Klein C, Michel PP, Ries V, Oertel WH, Alvarez-Fischer D. Wagner J, et al. Among authors: grunewald a. Neuroscience. 2017 Dec 4;365:137-145. doi: 10.1016/j.neuroscience.2017.09.045. Epub 2017 Oct 4. Neuroscience. 2017. PMID: 28987508
SLP-2 interacts with Parkin in mitochondria and prevents mitochondrial dysfunction in Parkin-deficient human iPSC-derived neurons and Drosophila.
Zanon A, Kalvakuri S, Rakovic A, Foco L, Guida M, Schwienbacher C, Serafin A, Rudolph F, Trilck M, Grünewald A, Stanslowsky N, Wegner F, Giorgio V, Lavdas AA, Bodmer R, Pramstaller PP, Klein C, Hicks AA, Pichler I, Seibler P. Zanon A, et al. Among authors: grunewald a. Hum Mol Genet. 2017 Jul 1;26(13):2412-2425. doi: 10.1093/hmg/ddx132. Hum Mol Genet. 2017. PMID: 28379402 Free PMC article.
161 results