Roep BO - Search Results

1

Plasmid-encoded proinsulin preserves C-peptide while specifically reducing proinsulin-specific CD8⁺ T cells in type 1 diabetes.

Roep BO, Solvason N, Gottlieb PA, Abreu JRF, Harrison LC, Eisenbarth GS, Yu L, Leviten M, Hagopian WA, Buse JB, von Herrath M, Quan J, King RS, Robinson WH, Utz PJ, Garren H; BHT-3021 Investigators; Steinman L. Roep BO, et al. Sci Transl Med. 2013 Jun 26;5(191):191ra82. doi: 10.1126/scitranslmed.3006103. Sci Transl Med. 2013. PMID: 23803704 Free PMC article. Clinical Trial.

2

T-cell reactivity to GAD65 peptide sequences shared with coxsackie virus protein in recent-onset IDDM, post-onset IDDM patients and control subjects.

Schloot NC, Roep BO, Wegmann DR, Yu L, Wang TB, Eisenbarth GS. Schloot NC, et al. Among authors: roep bo. Diabetologia. 1997 Mar;40(3):332-8. doi: 10.1007/s001250050683. Diabetologia. 1997. PMID: 9084973

3

Altered immune response to insulin in newly diagnosed compared to insulin-treated diabetic patients and healthy control subjects.

Schloot NC, Roep BO, Wegmann D, Yu L, Chase HP, Wang T, Eisenbarth GS. Schloot NC, et al. Among authors: roep bo. Diabetologia. 1997 May;40(5):564-72. doi: 10.1007/s001250050716. Diabetologia. 1997. PMID: 9165225

4

Autoreactive T cell responses in insulin-dependent (Type 1) diabetes mellitus. Report of the first international workshop for standardization of T cell assays.

Roep BO, Atkinson MA, van Endert PM, Gottlieb PA, Wilson SB, Sachs JA. Roep BO, et al. J Autoimmun. 1999 Sep;13(2):267-82. doi: 10.1006/jaut.1999.0312. J Autoimmun. 1999. PMID: 10479395

5

Molecular mimicry in type 1 diabetes mellitus revisited: T-cell clones to GAD65 peptides with sequence homology to Coxsackie or proinsulin peptides do not crossreact with homologous counterpart.

Schloot NC, Willemen SJ, Duinkerken G, Drijfhout JW, de Vries RR, Roep BO. Schloot NC, et al. Among authors: roep bo. Hum Immunol. 2001 Apr;62(4):299-309. doi: 10.1016/s0198-8859(01)00223-3. Hum Immunol. 2001. PMID: 11295462

6

Comparison of cytokine ELISpot assay formats for the detection of islet antigen autoreactive T cells. Report of the third immunology of diabetes society T-cell workshop.

Schloot NC, Meierhoff G, Karlsson Faresjö M, Ott P, Putnam A, Lehmann P, Gottlieb P, Roep BO, Peakman M, Tree T. Schloot NC, et al. Among authors: roep bo. J Autoimmun. 2003 Dec;21(4):365-76. doi: 10.1016/s0896-8411(03)00111-2. J Autoimmun. 2003. PMID: 14624759

7

Satisfaction (not) guaranteed: re-evaluating the use of animal models of type 1 diabetes.

Roep BO, Atkinson M, von Herrath M. Roep BO, et al. Nat Rev Immunol. 2004 Dec;4(12):989-97. doi: 10.1038/nri1502. Nat Rev Immunol. 2004. PMID: 15573133 Review.

8

T-cell assays to determine disease activity and clinical efficacy of immune therapy in type 1 diabetes.

van de Linde P, Roep BO. van de Linde P, et al. Among authors: roep bo. Am J Ther. 2005 Nov-Dec;12(6):573-9. doi: 10.1097/01.mjt.0000178768.44987.cb. Am J Ther. 2005. PMID: 16280651 Review.

9

Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes.

Pinkse GG, Tysma OH, Bergen CA, Kester MG, Ossendorp F, van Veelen PA, Keymeulen B, Pipeleers D, Drijfhout JW, Roep BO. Pinkse GG, et al. Among authors: roep bo. Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18425-30. doi: 10.1073/pnas.0508621102. Epub 2005 Dec 9. Proc Natl Acad Sci U S A. 2005. PMID: 16339897 Free PMC article.

10

Therapy with the hsp60 peptide DiaPep277 in C-peptide positive type 1 diabetes patients.

Huurman VA, Decochez K, Mathieu C, Cohen IR, Roep BO. Huurman VA, et al. Among authors: roep bo. Diabetes Metab Res Rev. 2007 May;23(4):269-75. doi: 10.1002/dmrr.691. Diabetes Metab Res Rev. 2007. PMID: 17024692 Clinical Trial.

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