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An Engineered Cytidine Deaminase for Biocatalytic Production of a Key Intermediate of the Covid-19 Antiviral Molnupiravir.
Burke AJ, Birmingham WR, Zhuo Y, Thorpe TW, Zucoloto da Costa B, Crawshaw R, Rowles I, Finnigan JD, Young C, Holgate GM, Muldowney MP, Charnock SJ, Lovelock SL, Turner NJ, Green AP. Burke AJ, et al. Among authors: rowles i. J Am Chem Soc. 2022 Mar 9;144(9):3761-3765. doi: 10.1021/jacs.1c11048. Epub 2022 Feb 28. J Am Chem Soc. 2022. PMID: 35224970 Free PMC article.