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Page 1
The Hedgehog signalling pathway regulates autophagy.
Jimenez-Sanchez M, Menzies FM, Chang YY, Simecek N, Neufeld TP, Rubinsztein DC. Jimenez-Sanchez M, et al. Among authors: simecek n. Nat Commun. 2012;3:1200. doi: 10.1038/ncomms2212. Nat Commun. 2012. PMID: 23149744 Free PMC article.
Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom.
Evans JC, Frayling TM, Cassell PG, Saker PJ, Hitman GA, Walker M, Levy JC, O'Rahilly S, Rao PV, Bennett AJ, Jones EC, Menzel S, Prestwich P, Simecek N, Wishart M, Dhillon R, Fletcher C, Millward A, Demaine A, Wilkin T, Horikawa Y, Cox NJ, Bell GI, Ellard S, McCarthy MI, Hattersley AT. Evans JC, et al. Among authors: simecek n. Am J Hum Genet. 2001 Sep;69(3):544-52. doi: 10.1086/323315. Epub 2001 Jul 31. Am J Hum Genet. 2001. PMID: 11481585 Free PMC article.
A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q.
Wiltshire S, Hattersley AT, Hitman GA, Walker M, Levy JC, Sampson M, O'Rahilly S, Frayling TM, Bell JI, Lathrop GM, Bennett A, Dhillon R, Fletcher C, Groves CJ, Jones E, Prestwich P, Simecek N, Rao PV, Wishart M, Bottazzo GF, Foxon R, Howell S, Smedley D, Cardon LR, Menzel S, McCarthy MI. Wiltshire S, et al. Among authors: simecek n. Am J Hum Genet. 2001 Sep;69(3):553-69. doi: 10.1086/323249. Epub 2001 Aug 1. Am J Hum Genet. 2001. PMID: 11484155 Free PMC article.
The neuroprotective action of the mood stabilizing drugs lithium chloride and sodium valproate is mediated through the up-regulation of the homeodomain protein Six1.
Plant KE, Anderson E, Simecek N, Brown R, Forster S, Spinks J, Toms N, Gibson GG, Lyon J, Plant N. Plant KE, et al. Among authors: simecek n. Toxicol Appl Pharmacol. 2009 Feb 15;235(1):124-34. doi: 10.1016/j.taap.2008.10.019. Epub 2008 Dec 6. Toxicol Appl Pharmacol. 2009. PMID: 19101580 Free article.