Dewson G - Search Results

1

Lymphotoxin α induces apoptosis, necroptosis and inflammatory signals with the same potency as tumour necrosis factor.

Etemadi N, Holien JK, Chau D, Dewson G, Murphy JM, Alexander WS, Parker MW, Silke J, Nachbur U. Etemadi N, et al. Among authors: dewson g. FEBS J. 2013 Nov;280(21):5283-97. doi: 10.1111/febs.12419. Epub 2013 Aug 2. FEBS J. 2013. PMID: 23815148 Free article.

2

RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.

Rickard JA, O'Donnell JA, Evans JM, Lalaoui N, Poh AR, Rogers T, Vince JE, Lawlor KE, Ninnis RL, Anderton H, Hall C, Spall SK, Phesse TJ, Abud HE, Cengia LH, Corbin J, Mifsud S, Di Rago L, Metcalf D, Ernst M, Dewson G, Roberts AW, Alexander WS, Murphy JM, Ekert PG, Masters SL, Vaux DL, Croker BA, Gerlic M, Silke J. Rickard JA, et al. Among authors: dewson g. Cell. 2014 May 22;157(5):1175-88. doi: 10.1016/j.cell.2014.04.019. Epub 2014 May 8. Cell. 2014. PMID: 24813849 Free article.

3

The Walrus and the Carpenter: Complex Regulation of Tumor Immunity in Colorectal Cancer.

Dewson G, Silke J. Dewson G, et al. Cell. 2018 Jun 28;174(1):14-16. doi: 10.1016/j.cell.2018.06.009. Cell. 2018. PMID: 29958104 Free article.

4

BAK core dimers bind lipids and can be bridged by them.

Cowan AD, Smith NA, Sandow JJ, Kapp EA, Rustam YH, Murphy JM, Brouwer JM, Bernardini JP, Roy MJ, Wardak AZ, Tan IK, Webb AI, Gulbis JM, Smith BJ, Reid GE, Dewson G, Colman PM, Czabotar PE. Cowan AD, et al. Among authors: dewson g. Nat Struct Mol Biol. 2020 Nov;27(11):1024-1031. doi: 10.1038/s41594-020-0494-5. Epub 2020 Sep 14. Nat Struct Mol Biol. 2020. PMID: 32929280

5

To trigger apoptosis, Bak exposes its BH3 domain and homodimerizes via BH3:groove interactions.

Dewson G, Kratina T, Sim HW, Puthalakath H, Adams JM, Colman PM, Kluck RM. Dewson G, et al. Mol Cell. 2008 May 9;30(3):369-80. doi: 10.1016/j.molcel.2008.04.005. Mol Cell. 2008. PMID: 18471982 Free article.

6

Bax dimerizes via a symmetric BH3:groove interface during apoptosis.

Dewson G, Ma S, Frederick P, Hockings C, Tan I, Kratina T, Kluck RM. Dewson G, et al. Cell Death Differ. 2012 Apr;19(4):661-70. doi: 10.1038/cdd.2011.138. Epub 2011 Oct 21. Cell Death Differ. 2012. PMID: 22015607 Free PMC article.

7

Bax crystal structures reveal how BH3 domains activate Bax and nucleate its oligomerization to induce apoptosis.

Czabotar PE, Westphal D, Dewson G, Ma S, Hockings C, Fairlie WD, Lee EF, Yao S, Robin AY, Smith BJ, Huang DC, Kluck RM, Adams JM, Colman PM. Czabotar PE, et al. Among authors: dewson g. Cell. 2013 Jan 31;152(3):519-31. doi: 10.1016/j.cell.2012.12.031. Cell. 2013. PMID: 23374347 Free article.

8

Characterizing Bcl-2 Family Protein Conformation and Oligomerization Using Cross-Linking and Antibody Gel-Shift in Conjunction with Native PAGE.

Dewson G. Dewson G. Methods Mol Biol. 2016;1419:185-96. doi: 10.1007/978-1-4939-3581-9_14. Methods Mol Biol. 2016. PMID: 27108440

9

Too much death can kill you: inhibiting intrinsic apoptosis to treat disease.

Li K, van Delft MF, Dewson G. Li K, et al. Among authors: dewson g. EMBO J. 2021 Jul 15;40(14):e107341. doi: 10.15252/embj.2020107341. Epub 2021 May 26. EMBO J. 2021. PMID: 34037273 Free PMC article. Review.

10

Mesenchymal stromal cell apoptosis is required for their therapeutic function.

Pang SHM, D'Rozario J, Mendonca S, Bhuvan T, Payne NL, Zheng D, Hisana A, Wallis G, Barugahare A, Powell D, Rautela J, Huntington ND, Dewson G, Huang DCS, Gray DHD, Heng TSP. Pang SHM, et al. Among authors: dewson g. Nat Commun. 2021 Nov 11;12(1):6495. doi: 10.1038/s41467-021-26834-3. Nat Commun. 2021. PMID: 34764248 Free PMC article.

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