Südhof TC - Search Results

1

Ultrahigh-resolution imaging reveals formation of neuronal SNARE/Munc18 complexes in situ.

Pertsinidis A, Mukherjee K, Sharma M, Pang ZP, Park SR, Zhang Y, Brunger AT, Südhof TC, Chu S. Pertsinidis A, et al. Among authors: sudhof tc. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):E2812-20. doi: 10.1073/pnas.1310654110. Epub 2013 Jul 2. Proc Natl Acad Sci U S A. 2013. PMID: 23821748 Free PMC article.

2

Testing the SNARE/SM protein model of membrane fusion.

Bacaj T, Pang ZP, Südhof TC. Bacaj T, et al. Among authors: sudhof tc. Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22365-6. doi: 10.1073/pnas.1017268108. Epub 2010 Dec 17. Proc Natl Acad Sci U S A. 2010. PMID: 21169506 Free PMC article. No abstract available.

3

α-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation.

Burré J, Sharma M, Südhof TC. Burré J, et al. Among authors: sudhof tc. Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):E4274-83. doi: 10.1073/pnas.1416598111. Epub 2014 Sep 22. Proc Natl Acad Sci U S A. 2014. PMID: 25246573 Free PMC article.

4

C-terminal domain of mammalian complexin-1 localizes to highly curved membranes.

Gong J, Lai Y, Li X, Wang M, Leitz J, Hu Y, Zhang Y, Choi UB, Cipriano D, Pfuetzner RA, Südhof TC, Yang X, Brunger AT, Diao J. Gong J, et al. Among authors: sudhof tc. Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7590-E7599. doi: 10.1073/pnas.1609917113. Epub 2016 Nov 7. Proc Natl Acad Sci U S A. 2016. PMID: 27821736 Free PMC article.

5

The primed SNARE-complexin-synaptotagmin complex for neuronal exocytosis.

Zhou Q, Zhou P, Wang AL, Wu D, Zhao M, Südhof TC, Brunger AT. Zhou Q, et al. Among authors: sudhof tc. Nature. 2017 Aug 24;548(7668):420-425. doi: 10.1038/nature23484. Epub 2017 Aug 16. Nature. 2017. PMID: 28813412 Free PMC article.

6

Lipid-anchored SNAREs lacking transmembrane regions fully support membrane fusion during neurotransmitter release.

Zhou P, Bacaj T, Yang X, Pang ZP, Südhof TC. Zhou P, et al. Among authors: sudhof tc. Neuron. 2013 Oct 16;80(2):470-83. doi: 10.1016/j.neuron.2013.09.010. Epub 2013 Oct 10. Neuron. 2013. PMID: 24120845 Free PMC article.

7

Complexin controls the force transfer from SNARE complexes to membranes in fusion.

Maximov A, Tang J, Yang X, Pang ZP, Südhof TC. Maximov A, et al. Among authors: sudhof tc. Science. 2009 Jan 23;323(5913):516-21. doi: 10.1126/science.1166505. Science. 2009. PMID: 19164751 Free PMC article.

8

CSPα promotes SNARE-complex assembly by chaperoning SNAP-25 during synaptic activity.

Sharma M, Burré J, Südhof TC. Sharma M, et al. Among authors: sudhof tc. Nat Cell Biol. 2011 Jan;13(1):30-9. doi: 10.1038/ncb2131. Epub 2010 Dec 12. Nat Cell Biol. 2011. PMID: 21151134

9

Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2.

Diao J, Burré J, Vivona S, Cipriano DJ, Sharma M, Kyoung M, Südhof TC, Brunger AT. Diao J, et al. Among authors: sudhof tc. Elife. 2013 Apr 30;2:e00592. doi: 10.7554/eLife.00592. Elife. 2013. PMID: 23638301 Free PMC article.

10

Architecture of the synaptotagmin-SNARE machinery for neuronal exocytosis.

Zhou Q, Lai Y, Bacaj T, Zhao M, Lyubimov AY, Uervirojnangkoorn M, Zeldin OB, Brewster AS, Sauter NK, Cohen AE, Soltis SM, Alonso-Mori R, Chollet M, Lemke HT, Pfuetzner RA, Choi UB, Weis WI, Diao J, Südhof TC, Brunger AT. Zhou Q, et al. Among authors: sudhof tc. Nature. 2015 Sep 3;525(7567):62-7. doi: 10.1038/nature14975. Epub 2015 Aug 17. Nature. 2015. PMID: 26280336 Free PMC article.

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