Koellhoffer JF - Search Results

1

Role of electrostatic repulsion in controlling pH-dependent conformational changes of viral fusion proteins.

Harrison JS, Higgins CD, O'Meara MJ, Koellhoffer JF, Kuhlman BA, Lai JR. Harrison JS, et al. Among authors: koellhoffer jf. Structure. 2013 Jul 2;21(7):1085-96. doi: 10.1016/j.str.2013.05.009. Structure. 2013. PMID: 23823327 Free PMC article. Review.

2

Marburg virus glycoprotein GP2: pH-dependent stability of the ectodomain α-helical bundle.

Harrison JS, Koellhoffer JF, Chandran K, Lai JR. Harrison JS, et al. Among authors: koellhoffer jf. Biochemistry. 2012 Mar 27;51(12):2515-25. doi: 10.1021/bi3000353. Epub 2012 Mar 12. Biochemistry. 2012. PMID: 22369502 Free PMC article.

3

Crystal structure of the Marburg virus GP2 core domain in its postfusion conformation.

Koellhoffer JF, Malashkevich VN, Harrison JS, Toro R, Bhosle RC, Chandran K, Almo SC, Lai JR. Koellhoffer JF, et al. Biochemistry. 2012 Oct 2;51(39):7665-75. doi: 10.1021/bi300976m. Epub 2012 Sep 19. Biochemistry. 2012. PMID: 22935026 Free PMC article.

4

C-peptide inhibitors of Ebola virus glycoprotein-mediated cell entry: effects of conjugation to cholesterol and side chain-side chain crosslinking.

Higgins CD, Koellhoffer JF, Chandran K, Lai JR. Higgins CD, et al. Among authors: koellhoffer jf. Bioorg Med Chem Lett. 2013 Oct 1;23(19):5356-60. doi: 10.1016/j.bmcl.2013.07.056. Epub 2013 Aug 2. Bioorg Med Chem Lett. 2013. PMID: 23962564 Free PMC article.

5

Protein engineering strategies for the development of viral vaccines and immunotherapeutics.

Koellhoffer JF, Higgins CD, Lai JR. Koellhoffer JF, et al. FEBS Lett. 2014 Jan 21;588(2):298-307. doi: 10.1016/j.febslet.2013.10.014. Epub 2013 Oct 21. FEBS Lett. 2014. PMID: 24157357 Free PMC article. Review.

6

Structural characterization of the glycoprotein GP2 core domain from the CAS virus, a novel arenavirus-like species.

Koellhoffer JF, Dai Z, Malashkevich VN, Stenglein MD, Liu Y, Toro R, S Harrison J, Chandran K, DeRisi JL, Almo SC, Lai JR. Koellhoffer JF, et al. J Mol Biol. 2014 Apr 3;426(7):1452-68. doi: 10.1016/j.jmb.2013.12.009. Epub 2013 Dec 12. J Mol Biol. 2014. PMID: 24333483 Free PMC article.

7

Two synthetic antibodies that recognize and neutralize distinct proteolytic forms of the ebola virus envelope glycoprotein.

Koellhoffer JF, Chen G, Sandesara RG, Bale S, Saphire EO, Chandran K, Sidhu SS, Lai JR. Koellhoffer JF, et al. Chembiochem. 2012 Nov 26;13(17):2549-57. doi: 10.1002/cbic.201200493. Epub 2012 Oct 30. Chembiochem. 2012. PMID: 23111988 Free PMC article.

8

Conformational properties of peptides corresponding to the ebolavirus GP2 membrane-proximal external region in the presence of micelle-forming surfactants and lipids.

Regula LK, Harris R, Wang F, Higgins CD, Koellhoffer JF, Zhao Y, Chandran K, Gao J, Girvin ME, Lai JR. Regula LK, et al. Among authors: koellhoffer jf. Biochemistry. 2013 May 21;52(20):3393-404. doi: 10.1021/bi400040v. Epub 2013 May 7. Biochemistry. 2013. PMID: 23650881 Free PMC article.

9

Synthetic antibodies with a human framework that protect mice from lethal Sudan ebolavirus challenge.

Chen G, Koellhoffer JF, Zak SE, Frei JC, Liu N, Long H, Ye W, Nagar K, Pan G, Chandran K, Dye JM, Sidhu SS, Lai JR. Chen G, et al. Among authors: koellhoffer jf. ACS Chem Biol. 2014 Oct 17;9(10):2263-73. doi: 10.1021/cb5006454. Epub 2014 Aug 26. ACS Chem Biol. 2014. PMID: 25140871 Free PMC article.

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