Shatz W - Search Results

1

Bispecific antibodies with natural architecture produced by co-culture of bacteria expressing two distinct half-antibodies.

Spiess C, Merchant M, Huang A, Zheng Z, Yang NY, Peng J, Ellerman D, Shatz W, Reilly D, Yansura DG, Scheer JM. Spiess C, et al. Among authors: shatz w. Nat Biotechnol. 2013 Aug;31(8):753-8. doi: 10.1038/nbt.2621. Epub 2013 Jul 7. Nat Biotechnol. 2013. PMID: 23831709

2

Development of a human IgG4 bispecific antibody for dual targeting of interleukin-4 (IL-4) and interleukin-13 (IL-13) cytokines.

Spiess C, Bevers J 3rd, Jackman J, Chiang N, Nakamura G, Dillon M, Liu H, Molina P, Elliott JM, Shatz W, Scheer JM, Giese G, Persson J, Zhang Y, Dennis MS, Giulianotti J, Gupta P, Reilly D, Palma E, Wang J, Stefanich E, Scheerens H, Fuh G, Wu LC. Spiess C, et al. Among authors: shatz w. J Biol Chem. 2013 Sep 13;288(37):26583-93. doi: 10.1074/jbc.M113.480483. Epub 2013 Jul 23. J Biol Chem. 2013. PMID: 23880771 Free PMC article.

3

Knobs-into-holes antibody production in mammalian cell lines reveals that asymmetric afucosylation is sufficient for full antibody-dependent cellular cytotoxicity.

Shatz W, Chung S, Li B, Marshall B, Tejada M, Phung W, Sandoval W, Kelley RF, Scheer JM. Shatz W, et al. MAbs. 2013 Nov-Dec;5(6):872-81. doi: 10.4161/mabs.26307. Epub 2013 Aug 29. MAbs. 2013. PMID: 23995614 Free PMC article.

4

An efficient route to bispecific antibody production using single-reactor mammalian co-culture.

Shatz W, Ng D, Dutina G, Wong AW, Dunshee DR, Sonoda J, Shen A, Scheer JM. Shatz W, et al. MAbs. 2016 Nov/Dec;8(8):1487-1497. doi: 10.1080/19420862.2016.1234569. MAbs. 2016. PMID: 27680183 Free PMC article.

5

Design and Pharmacokinetic Characterization of Novel Antibody Formats for Ocular Therapeutics.

Gadkar K, Pastuskovas CV, Le Couter JE, Elliott JM, Zhang J, Lee CV, Sanowar S, Fuh G, Kim HS, Lombana TN, Spiess C, Nakamura M, Hass P, Shatz W, Meng YG, Scheer JM. Gadkar K, et al. Among authors: shatz w. Invest Ophthalmol Vis Sci. 2015 Aug;56(9):5390-400. doi: 10.1167/iovs.15-17108. Invest Ophthalmol Vis Sci. 2015. PMID: 26275136

6

Protein engineering to increase the potential of a therapeutic antibody Fab for long-acting delivery to the eye.

Tesar D, Luoma J, Wyatt EA, Shi C, Shatz W, Hass PE, Mathieu M, Yi L, Corn JE, Maass KF, Wang K, Dion MZ, Andersen N, Loyet KM, van Lookeren Campagne M, Rajagopal K, Dickmann L, Scheer JM, Kelley RF. Tesar D, et al. Among authors: shatz w. MAbs. 2017 Nov/Dec;9(8):1297-1305. doi: 10.1080/19420862.2017.1372078. Epub 2017 Aug 30. MAbs. 2017. PMID: 28854082 Free PMC article.

7

Contribution of Antibody Hydrodynamic Size to Vitreal Clearance Revealed through Rabbit Studies Using a Species-Matched Fab.

Shatz W, Hass PE, Mathieu M, Kim HS, Leach K, Zhou M, Crawford Y, Shen A, Wang K, Chang DP, Maia M, Crowell SR, Dickmann L, Scheer JM, Kelley RF. Shatz W, et al. Mol Pharm. 2016 Sep 6;13(9):2996-3003. doi: 10.1021/acs.molpharmaceut.6b00345. Epub 2016 Jun 14. Mol Pharm. 2016. PMID: 27244474

8

Identification and characterization of an octameric PEG-protein conjugate system for intravitreal long-acting delivery to the back of the eye.

Shatz W, Hass PE, Peer N, Paluch MT, Blanchette C, Han G, Sandoval W, Morando A, Loyet KM, Bantseev V, Booler H, Crowell S, Kamath A, Scheer JM, Kelley RF. Shatz W, et al. PLoS One. 2019 Jun 28;14(6):e0218613. doi: 10.1371/journal.pone.0218613. eCollection 2019. PLoS One. 2019. PMID: 31251757 Free PMC article.

9

Data on charge separation of bispecific and mispaired IgGs using native charge-variant mass spectrometry.

Phung W, Han G, Polderdijk SGI, Dillon M, Shatz W, Liu P, Wei B, Suresh P, Fischer D, Spiess C, Bailey A, Carter PJ, Lill JR, Sandoval W. Phung W, et al. Among authors: shatz w. Data Brief. 2020 Mar 16;30:105435. doi: 10.1016/j.dib.2020.105435. eCollection 2020 Jun. Data Brief. 2020. PMID: 32274410 Free PMC article.

10

In Vivo Stability Profiles of Anti-factor D Molecules Support Long-Acting Delivery Approaches.

Loyet KM, Hass PE, Sandoval WN, Morando A, Liu P, Shatz W, Dickmann L, Kenrick M, Good J, Davancaze T, Morimoto AM, Kelley RF, Scheer JM. Loyet KM, et al. Among authors: shatz w. Mol Pharm. 2019 Jan 7;16(1):86-95. doi: 10.1021/acs.molpharmaceut.8b00871. Epub 2018 Dec 3. Mol Pharm. 2019. PMID: 30444371

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