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Multiwalled carbon nanotubes intratracheally instilled into the rat lung induce development of pleural malignant mesothelioma and lung tumors.
Suzui M, Futakuchi M, Fukamachi K, Numano T, Abdelgied M, Takahashi S, Ohnishi M, Omori T, Tsuruoka S, Hirose A, Kanno J, Sakamoto Y, Alexander DB, Alexander WT, Jiegou X, Tsuda H. Suzui M, et al. Among authors: numano t. Cancer Sci. 2016 Jul;107(7):924-35. doi: 10.1111/cas.12954. Epub 2016 Jun 23. Cancer Sci. 2016. PMID: 27098557 Free PMC article.
Potassium octatitanate fibers induce persistent lung and pleural injury and are possibly carcinogenic in male Fischer 344 rats.
Abdelgied M, El-Gazzar AM, Alexander DB, Alexander WT, Numano T, Iigou M, Naiki-Ito A, Takase H, Abdou KA, Hirose A, Taquahashi Y, Kanno J, Tsuda H, Takahashi S. Abdelgied M, et al. Among authors: numano t. Cancer Sci. 2018 Jul;109(7):2164-2177. doi: 10.1111/cas.13643. Epub 2018 Jun 22. Cancer Sci. 2018. PMID: 29774637 Free PMC article.
Comparative pulmonary toxicity of a DWCNT and MWCNT-7 in rats.
El-Gazzar AM, Abdelgied M, Alexander DB, Alexander WT, Numano T, Iigo M, Naiki A, Takahashi S, Takase H, Hirose A, Kannno J, Elokle OS, Nazem AM, Tsuda H. El-Gazzar AM, et al. Among authors: numano t. Arch Toxicol. 2019 Jan;93(1):49-59. doi: 10.1007/s00204-018-2336-3. Epub 2018 Oct 19. Arch Toxicol. 2019. PMID: 30341734 Free PMC article.
Pulmonary and pleural toxicity of potassium octatitanate fibers, rutile titanium dioxide nanoparticles, and MWCNT-7 in male Fischer 344 rats.
Abdelgied M, El-Gazzar AM, Alexander DB, Alexander WT, Numano T, Iigou M, Naiki-Ito A, Takase H, Abdou KA, Hirose A, Taquahashi Y, Kanno J, Abdelhamid M, Tsuda H, Takahashi S. Abdelgied M, et al. Among authors: numano t. Arch Toxicol. 2019 Apr;93(4):909-920. doi: 10.1007/s00204-019-02410-z. Epub 2019 Feb 13. Arch Toxicol. 2019. PMID: 30759267
Carcinogenic effect of potassium octatitanate (POT) fibers in the lung and pleura of male Fischer 344 rats after intrapulmonary administration.
Abdelgied M, El-Gazzar AM, Alexander WT, Numano T, Iigou M, Naiki-Ito A, Takase H, Hirose A, Taquahashi Y, Kanno J, Abdelhamid M, Abdou KA, Takahashi S, Alexander DB, Tsuda H. Abdelgied M, et al. Among authors: numano t. Part Fibre Toxicol. 2019 Sep 2;16(1):34. doi: 10.1186/s12989-019-0316-2. Part Fibre Toxicol. 2019. PMID: 31477126 Free PMC article.
Comparative carcinogenicity study of a thick, straight-type and a thin, tangled-type multi-walled carbon nanotube administered by intra-tracheal instillation in the rat.
Saleh DM, Alexander WT, Numano T, Ahmed OHM, Gunasekaran S, Alexander DB, Abdelgied M, El-Gazzar AM, Takase H, Xu J, Naiki-Ito A, Takahashi S, Hirose A, Ohnishi M, Kanno J, Tsuda H. Saleh DM, et al. Among authors: numano t. Part Fibre Toxicol. 2020 Oct 15;17(1):48. doi: 10.1186/s12989-020-00382-y. Part Fibre Toxicol. 2020. PMID: 33054855 Free PMC article.
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