Turnbull AV - Search Results

1

11-Dehydrocorticosterone causes metabolic syndrome, which is prevented when 11β-HSD1 is knocked out in livers of male mice.

Harno E, Cottrell EC, Keevil BG, DeSchoolmeester J, Bohlooly-Y M, Andersén H, Turnbull AV, Leighton B, White A. Harno E, et al. Among authors: turnbull av. Endocrinology. 2013 Oct;154(10):3599-609. doi: 10.1210/en.2013-1362. Epub 2013 Jul 5. Endocrinology. 2013. PMID: 23832962

2

11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors still improve metabolic phenotype in male 11β-HSD1 knockout mice suggesting off-target mechanisms.

Harno E, Cottrell EC, Yu A, DeSchoolmeester J, Gutierrez PM, Denn M, Swales JG, Goldberg FW, Bohlooly-Y M, Andersén H, Wild MJ, Turnbull AV, Leighton B, White A. Harno E, et al. Among authors: turnbull av. Endocrinology. 2013 Dec;154(12):4580-93. doi: 10.1210/en.2013-1613. Epub 2013 Oct 29. Endocrinology. 2013. PMID: 24169553 Free PMC article.

3

Pro-opiomelanocortin processing in the hypothalamus: impact on melanocortin signalling and obesity.

Pritchard LE, Turnbull AV, White A. Pritchard LE, et al. Among authors: turnbull av. J Endocrinol. 2002 Mar;172(3):411-21. doi: 10.1677/joe.0.1720411. J Endocrinol. 2002. PMID: 11874690 Review.

4

Proopiomelanocortin-derived peptides in rat cerebrospinal fluid and hypothalamic extracts: evidence that secretion is regulated with respect to energy balance.

Pritchard LE, Oliver RL, McLoughlin JD, Birtles S, Lawrence CB, Turnbull AV, White A. Pritchard LE, et al. Among authors: turnbull av. Endocrinology. 2003 Mar;144(3):760-6. doi: 10.1210/en.2002-220866. Endocrinology. 2003. PMID: 12586751

5

Optimization of brain penetrant 11β-hydroxysteroid dehydrogenase type I inhibitors and in vivo testing in diet-induced obese mice.

Goldberg FW, Dossetter AG, Scott JS, Robb GR, Boyd S, Groombridge SD, Kemmitt PD, Sjögren T, Gutierrez PM, deSchoolmeester J, Swales JG, Turnbull AV, Wild MJ. Goldberg FW, et al. Among authors: turnbull av. J Med Chem. 2014 Feb 13;57(3):970-86. doi: 10.1021/jm4016729. Epub 2014 Jan 27. J Med Chem. 2014. PMID: 24422550

6

Interleukin-6 is an afferent signal to the hypothalamo-pituitary-adrenal axis during local inflammation in mice.

Turnbull AV, Prehar S, Kennedy AR, Little RA, Hopkins SJ. Turnbull AV, et al. Endocrinology. 2003 May;144(5):1894-906. doi: 10.1210/en.2002-220964. Endocrinology. 2003. PMID: 12697697

7

Mechanisms of activation of the pituitary-adrenal axis by tissue injury in the rat.

Turnbull AV, Dow RC, Hopkins SJ, White A, Fink G, Rothwell NJ. Turnbull AV, et al. Psychoneuroendocrinology. 1994;19(2):165-78. doi: 10.1016/0306-4530(94)90006-x. Psychoneuroendocrinology. 1994. PMID: 8190836

8

Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 reduces food intake and weight gain but maintains energy expenditure in diet-induced obese mice.

Wang SJ, Birtles S, de Schoolmeester J, Swales J, Moody G, Hislop D, O'Dowd J, Smith DM, Turnbull AV, Arch JR. Wang SJ, et al. Among authors: turnbull av. Diabetologia. 2006 Jun;49(6):1333-7. doi: 10.1007/s00125-006-0239-y. Epub 2006 Apr 13. Diabetologia. 2006. PMID: 16612591

9

Glucagon challenge in the rat: a robust method for the in vivo assessment of Glycogen phosphorlyase inhibitor efficacy.

Loxham SJ, Teague J, Poucher SM, De Schoolmeester J, Turnbull AV, Carey F. Loxham SJ, et al. Among authors: turnbull av. J Pharmacol Toxicol Methods. 2007 Jan-Feb;55(1):71-7. doi: 10.1016/j.vascn.2006.03.005. Epub 2006 Mar 27. J Pharmacol Toxicol Methods. 2007. PMID: 16713718

10

CRF type I receptor-deficient mice exhibit a pronounced pituitary-adrenal response to local inflammation.

Turnbull AV, Smith GW, Lee S, Vale WW, Lee KF, Rivier C. Turnbull AV, et al. Endocrinology. 1999 Feb;140(2):1013-7. doi: 10.1210/endo.140.2.6675. Endocrinology. 1999. PMID: 9927337

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