Piazza GA - Search Results

1

6-Aryl and heterocycle quinazoline derivatives as potent EGFR inhibitors with improved activity toward gefitinib-sensitive and -resistant tumor cell lines.

Hamed MM, Abou El Ella DA, Keeton AB, Piazza GA, Abadi AH, Hartmann RW, Engel M. Hamed MM, et al. Among authors: piazza ga. ChemMedChem. 2013 Sep;8(9):1495-504. doi: 10.1002/cmdc.201300147. Epub 2013 Jul 11. ChemMedChem. 2013. PMID: 23847159

2

Suppression of Wnt/beta-catenin signaling inhibits prostate cancer cell proliferation.

Lu W, Tinsley HN, Keeton A, Qu Z, Piazza GA, Li Y. Lu W, et al. Among authors: piazza ga. Eur J Pharmacol. 2009 Jan 5;602(1):8-14. doi: 10.1016/j.ejphar.2008.10.053. Epub 2008 Nov 9. Eur J Pharmacol. 2009. PMID: 19026633 Free PMC article.

3

A novel sulindac derivative that does not inhibit cyclooxygenases but potently inhibits colon tumor cell growth and induces apoptosis with antitumor activity.

Piazza GA, Keeton AB, Tinsley HN, Gary BD, Whitt JD, Mathew B, Thaiparambil J, Coward L, Gorman G, Li Y, Sani B, Hobrath JV, Maxuitenko YY, Reynolds RC. Piazza GA, et al. Cancer Prev Res (Phila). 2009 Jun;2(6):572-80. doi: 10.1158/1940-6207.CAPR-09-0001. Epub 2009 May 26. Cancer Prev Res (Phila). 2009. PMID: 19470791 Free PMC article.

4

Design, synthesis and biological evaluation of novel pyridine derivatives as anticancer agents and phosphodiesterase 3 inhibitors.

Abadi AH, Ibrahim TM, Abouzid KM, Lehmann J, Tinsley HN, Gary BD, Piazza GA. Abadi AH, et al. Among authors: piazza ga. Bioorg Med Chem. 2009 Aug 15;17(16):5974-82. doi: 10.1016/j.bmc.2009.06.063. Epub 2009 Jul 3. Bioorg Med Chem. 2009. PMID: 19628397 Free PMC article.

5

Synthesis of novel tadalafil analogues and their evaluation as phosphodiesterase inhibitors and anticancer agents.

Abadi AH, Abouel-Ella DA, Ahmed NS, Gary BD, Thaiparambil JT, Tinsley HN, Keeton AB, Piazza GA. Abadi AH, et al. Among authors: piazza ga. Arzneimittelforschung. 2009;59(8):415-21. doi: 10.1055/s-0031-1296417. Arzneimittelforschung. 2009. PMID: 19813465 Free PMC article.

6

Discovery of colon tumor cell growth inhibitory agents through a combinatorial approach.

Abadi AH, Abouel-Ella DA, Lehmann J, Tinsley HN, Gary BD, Piazza GA, Abdel-Fattah MA. Abadi AH, et al. Among authors: piazza ga. Eur J Med Chem. 2010 Jan;45(1):90-7. doi: 10.1016/j.ejmech.2009.09.029. Epub 2009 Sep 20. Eur J Med Chem. 2010. PMID: 19836860 Free PMC article.

7

Sulindac sulfide selectively inhibits growth and induces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of protein kinase G.

Tinsley HN, Gary BD, Keeton AB, Zhang W, Abadi AH, Reynolds RC, Piazza GA. Tinsley HN, et al. Among authors: piazza ga. Mol Cancer Ther. 2009 Dec;8(12):3331-40. doi: 10.1158/1535-7163.MCT-09-0758. Mol Cancer Ther. 2009. PMID: 19996273 Free PMC article.

8

Synthesis, molecular modeling and biological evaluation of novel tadalafil analogues as phosphodiesterase 5 and colon tumor cell growth inhibitors, new stereochemical perspective.

Abadi AH, Gary BD, Tinsley HN, Piazza GA, Abdel-Halim M. Abadi AH, et al. Among authors: piazza ga. Eur J Med Chem. 2010 Apr;45(4):1278-86. doi: 10.1016/j.ejmech.2009.10.046. Eur J Med Chem. 2010. PMID: 20206015 Free PMC article.

9

Colon tumor cell growth-inhibitory activity of sulindac sulfide and other nonsteroidal anti-inflammatory drugs is associated with phosphodiesterase 5 inhibition.

Tinsley HN, Gary BD, Thaiparambil J, Li N, Lu W, Li Y, Maxuitenko YY, Keeton AB, Piazza GA. Tinsley HN, et al. Among authors: piazza ga. Cancer Prev Res (Phila). 2010 Oct;3(10):1303-13. doi: 10.1158/1940-6207.CAPR-10-0030. Epub 2010 Sep 28. Cancer Prev Res (Phila). 2010. PMID: 20876730 Free PMC article.

10

A novel access to arylated and heteroarylated beta-carboline based PDE5 inhibitors.

Ahmed NS, Gary BD, Piazza GA, Tinsley HN, Laufer S, Abadi AH. Ahmed NS, et al. Among authors: piazza ga. Med Chem. 2010 Nov;6(6):374-87. doi: 10.2174/157340610793563992. Med Chem. 2010. PMID: 21054274 Free PMC article.

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