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Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma.
Jiang X, Hao HX, Growney JD, Woolfenden S, Bottiglio C, Ng N, Lu B, Hsieh MH, Bagdasarian L, Meyer R, Smith TR, Avello M, Charlat O, Xie Y, Porter JA, Pan S, Liu J, McLaughlin ME, Cong F. Jiang X, et al. Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12649-54. doi: 10.1073/pnas.1307218110. Epub 2013 Jul 11. Proc Natl Acad Sci U S A. 2013. PMID: 23847203 Free PMC article.
Interaction with both ZNRF3 and LGR4 is required for the signalling activity of R-spondin.
Xie Y, Zamponi R, Charlat O, Ramones M, Swalley S, Jiang X, Rivera D, Tschantz W, Lu B, Quinn L, Dimitri C, Parker J, Jeffery D, Wilcox SK, Watrobka M, LeMotte P, Granda B, Porter JA, Myer VE, Loew A, Cong F. Xie Y, et al. Among authors: jiang x. EMBO Rep. 2013 Dec;14(12):1120-6. doi: 10.1038/embor.2013.167. Epub 2013 Oct 29. EMBO Rep. 2013. PMID: 24165923 Free PMC article.
USP7 inhibits Wnt/β-catenin signaling through promoting stabilization of Axin.
Ji L, Lu B, Zamponi R, Charlat O, Aversa R, Yang Z, Sigoillot F, Zhu X, Hu T, Reece-Hoyes JS, Russ C, Michaud G, Tchorz JS, Jiang X, Cong F. Ji L, et al. Among authors: jiang x. Nat Commun. 2019 Sep 13;10(1):4184. doi: 10.1038/s41467-019-12143-3. Nat Commun. 2019. PMID: 31519875 Free PMC article.
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