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Polyadenylation site-induced decay of upstream transcripts enforces promoter directionality.
Ntini E, Järvelin AI, Bornholdt J, Chen Y, Boyd M, Jørgensen M, Andersson R, Hoof I, Schein A, Andersen PR, Andersen PK, Preker P, Valen E, Zhao X, Pelechano V, Steinmetz LM, Sandelin A, Jensen TH. Ntini E, et al. Among authors: pelechano v. Nat Struct Mol Biol. 2013 Aug;20(8):923-8. doi: 10.1038/nsmb.2640. Epub 2013 Jul 14. Nat Struct Mol Biol. 2013. PMID: 23851456
Functional consequences of bidirectional promoters.
Wei W, Pelechano V, Järvelin AI, Steinmetz LM. Wei W, et al. Among authors: pelechano v. Trends Genet. 2011 Jul;27(7):267-76. doi: 10.1016/j.tig.2011.04.002. Epub 2011 May 24. Trends Genet. 2011. PMID: 21601935 Free PMC article. Review.
Genome-wide polyadenylation site mapping.
Pelechano V, Wilkening S, Järvelin AI, Tekkedil MM, Steinmetz LM. Pelechano V, et al. Methods Enzymol. 2012;513:271-96. doi: 10.1016/B978-0-12-391938-0.00012-4. Methods Enzymol. 2012. PMID: 22929774
Gene regulation by antisense transcription.
Pelechano V, Steinmetz LM. Pelechano V, et al. Nat Rev Genet. 2013 Dec;14(12):880-93. doi: 10.1038/nrg3594. Epub 2013 Nov 12. Nat Rev Genet. 2013. PMID: 24217315 Review.
83 results