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Pain and other non-neurological adverse events in children with sickle cell anemia and previous stroke who received hydroxyurea and phlebotomy or chronic transfusions and chelation: results from the SWiTCH clinical trial.
Alvarez O, Yovetich NA, Scott JP, Owen W, Miller ST, Schultz W, Lockhart A, Aygun B, Flanagan J, Bonner M, Mueller BU, Ware RE; Investigators of the Stroke With Transfusions Changing to Hydroxyurea Clinical Trial (SWiTCH). Alvarez O, et al. Among authors: lockhart a. Am J Hematol. 2013 Nov;88(11):932-8. doi: 10.1002/ajh.23547. Epub 2013 Aug 30. Am J Hematol. 2013. PMID: 23861242 Free PMC article. Clinical Trial.
Therapeutic phlebotomy is safe in children with sickle cell anaemia and can be effective treatment for transfusional iron overload.
Aygun B, Mortier NA, Kesler K, Lockhart A, Schultz WH, Cohen AR, Alvarez O, Rogers ZR, Kwiatkowski JL, Miller ST, Sylvestre P, Iyer R, Lane PA, Ware RE; Stroke With Transfusions Changing to Hydroxyurea (SWiTCH) Trial Investigators. Aygun B, et al. Among authors: lockhart a. Br J Haematol. 2015 Apr;169(2):262-6. doi: 10.1111/bjh.13280. Epub 2015 Jan 22. Br J Haematol. 2015. PMID: 25612463 Free PMC article. Clinical Trial.
Stimulating Soluble Guanylyl Cyclase with the Clinical Agonist Riociguat Restrains the Development and Progression of Castration-Resistant Prostate Cancer.
Zhang L, Troccoli CI, Mateo-Victoriano B, Misiara Lincheta L, Jackson E, Shu P, Plastini T, Tao W, Kwon D, Chen XS, Sharma J, Jorda M, Kumar S, Lombard DB, Gulley JL, Bilusic M, Lockhart AC, Beuve A, Rai P. Zhang L, et al. Among authors: lockhart ac. Cancer Res. 2025 Jan 2;85(1):134-153. doi: 10.1158/0008-5472.CAN-24-0133. Cancer Res. 2025. PMID: 39388307
Large-scale analysis of CDH1 mutations defines a distinctive molecular subset with treatment implications in gastric cancer.
Wang J, Xiu J, Battaglin F, Arai H, Soni S, Zhang W, Goldberg RM, Philip PA, Seeber A, Hwang JJ, Shields AF, Marshall JL, Astaturov I, Liu T, Lockhart AC, Korn WM, Shen L, Lenz HJ. Wang J, et al. Among authors: lockhart ac. NPJ Precis Oncol. 2024 Sep 30;8(1):214. doi: 10.1038/s41698-024-00694-8. NPJ Precis Oncol. 2024. PMID: 39349771 Free PMC article.
476 results