Jumaa H - Search Results

1

Insulin-like growth factor-1 receptor (IGF1R) as a novel target in chronic lymphocytic leukemia.

Yaktapour N, Übelhart R, Schüler J, Aumann K, Dierks C, Burger M, Pfeifer D, Jumaa H, Veelken H, Brummer T, Zirlik K. Yaktapour N, et al. Among authors: jumaa h. Blood. 2013 Aug 29;122(9):1621-33. doi: 10.1182/blood-2013-02-484386. Epub 2013 Jul 17. Blood. 2013. PMID: 23863897 Free article.

2

The adaptor protein SLP-65 acts as a tumor suppressor that limits pre-B cell expansion.

Flemming A, Brummer T, Reth M, Jumaa H. Flemming A, et al. Among authors: jumaa h. Nat Immunol. 2003 Jan;4(1):38-43. doi: 10.1038/ni862. Epub 2002 Nov 18. Nat Immunol. 2003. PMID: 12436112

3

Spleen tyrosine kinase is overexpressed and represents a potential therapeutic target in chronic lymphocytic leukemia.

Buchner M, Fuchs S, Prinz G, Pfeifer D, Bartholomé K, Burger M, Chevalier N, Vallat L, Timmer J, Gribben JG, Jumaa H, Veelken H, Dierks C, Zirlik K. Buchner M, et al. Among authors: jumaa h. Cancer Res. 2009 Jul 1;69(13):5424-32. doi: 10.1158/0008-5472.CAN-08-4252. Epub 2009 Jun 23. Cancer Res. 2009. PMID: 19549911

4

Spleen tyrosine kinase inhibition prevents chemokine- and integrin-mediated stromal protective effects in chronic lymphocytic leukemia.

Buchner M, Baer C, Prinz G, Dierks C, Burger M, Zenz T, Stilgenbauer S, Jumaa H, Veelken H, Zirlik K. Buchner M, et al. Among authors: jumaa h. Blood. 2010 Jun 3;115(22):4497-506. doi: 10.1182/blood-2009-07-233692. Epub 2010 Mar 24. Blood. 2010. PMID: 20335218 Free article.

5

N-linked glycosylation selectively regulates autonomous precursor BCR function.

Ubelhart R, Bach MP, Eschbach C, Wossning T, Reth M, Jumaa H. Ubelhart R, et al. Among authors: jumaa h. Nat Immunol. 2010 Aug;11(8):759-65. doi: 10.1038/ni.1903. Epub 2010 Jul 11. Nat Immunol. 2010. PMID: 20622883

6

Trisomy 12 and elevated GLI1 and PTCH1 transcript levels are biomarkers for Hedgehog-inhibitor responsiveness in CLL.

Decker S, Zirlik K, Djebatchie L, Hartmann D, Ihorst G, Schmitt-Graeff A, Herchenbach D, Jumaa H, Warmuth M, Veelken H, Dierks C. Decker S, et al. Among authors: jumaa h. Blood. 2012 Jan 26;119(4):997-1007. doi: 10.1182/blood-2011-06-359075. Epub 2011 Nov 30. Blood. 2012. PMID: 22130798 Free article.

7

Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling.

Dühren-von Minden M, Übelhart R, Schneider D, Wossning T, Bach MP, Buchner M, Hofmann D, Surova E, Follo M, Köhler F, Wardemann H, Zirlik K, Veelken H, Jumaa H. Dühren-von Minden M, et al. Among authors: jumaa h. Nature. 2012 Sep 13;489(7415):309-12. doi: 10.1038/nature11309. Nature. 2012. PMID: 22885698

8

SOX4 enables oncogenic survival signals in acute lymphoblastic leukemia.

Ramezani-Rad P, Geng H, Hurtz C, Chan LN, Chen Z, Jumaa H, Melnick A, Paietta E, Carroll WL, Willman CL, Lefebvre V, Müschen M. Ramezani-Rad P, et al. Among authors: jumaa h. Blood. 2013 Jan 3;121(1):148-55. doi: 10.1182/blood-2012-05-428938. Epub 2012 Nov 14. Blood. 2013. PMID: 23152540 Free PMC article.

9

Premature terminal differentiation protects from deregulated lymphocyte activation by ITK-Syk.

Bach MP, Hug E, Werner M, Holch J, Sprissler C, Pechloff K, Zirlik K, Zeiser R, Dierks C, Ruland J, Jumaa H. Bach MP, et al. Among authors: jumaa h. J Immunol. 2014 Feb 1;192(3):1024-33. doi: 10.4049/jimmunol.1300420. Epub 2013 Dec 27. J Immunol. 2014. PMID: 24376268

10

PIM kinases are essential for chronic lymphocytic leukemia cell survival (PIM2/3) and CXCR4-mediated microenvironmental interactions (PIM1).

Decker S, Finter J, Forde AJ, Kissel S, Schwaller J, Mack TS, Kuhn A, Gray N, Follo M, Jumaa H, Burger M, Zirlik K, Pfeifer D, Miduturu CV, Eibel H, Veelken H, Dierks C. Decker S, et al. Among authors: jumaa h. Mol Cancer Ther. 2014 May;13(5):1231-45. doi: 10.1158/1535-7163.MCT-13-0575-T. Epub 2014 Mar 21. Mol Cancer Ther. 2014. PMID: 24659821

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