Bracke ME - Search Results

1

Design, synthesis and structure-activity relationships of some novel, highly potent anti-invasive (E)- and (Z)-stilbenes.

Roman BI, De Coen LM, Thérèse F C Mortier S, De Ryck T, Vanhoecke BW, Katritzky AR, Bracke ME, Stevens CV. Roman BI, et al. Among authors: bracke me. Bioorg Med Chem. 2013 Sep 1;21(17):5054-63. doi: 10.1016/j.bmc.2013.06.048. Epub 2013 Jun 27. Bioorg Med Chem. 2013. PMID: 23867387

2

Further studies on anti-invasive chemotypes: An excursion from chalcones to curcuminoids.

Roman BI, De Ryck T, Verhasselt S, Bracke ME, Stevens CV. Roman BI, et al. Among authors: bracke me. Bioorg Med Chem Lett. 2015 Mar 1;25(5):1021-5. doi: 10.1016/j.bmcl.2015.01.027. Epub 2015 Jan 22. Bioorg Med Chem Lett. 2015. PMID: 25666820

3

Chick Heart Invasion Assay for Testing the Invasiveness of Cancer Cells and the Activity of Potentially Anti-invasive Compounds.

Bracke ME, Roman BI, Stevens CV, Mus LM, Parmar VS, De Wever O, Mareel MM. Bracke ME, et al. J Vis Exp. 2015 Jun 6;(100):e52792. doi: 10.3791/52792. J Vis Exp. 2015. PMID: 26131648 Free PMC article.

4

4-Fluoro-3',4',5'-trimethoxychalcone as a new anti-invasive agent. From discovery to initial validation in an in vivo metastasis model.

Roman BI, De Ryck T, Patronov A, Slavov SH, Vanhoecke BW, Katritzky AR, Bracke ME, Stevens CV. Roman BI, et al. Among authors: bracke me. Eur J Med Chem. 2015 Aug 28;101:627-39. doi: 10.1016/j.ejmech.2015.06.029. Epub 2015 Jul 10. Eur J Med Chem. 2015. PMID: 26204510

5

Improved synthesis and comparative analysis of the tool properties of new and existing D-ring modified (S)-blebbistatin analogs.

Verhasselt S, Roman BI, Bracke ME, Stevens CV. Verhasselt S, et al. Among authors: bracke me. Eur J Med Chem. 2017 Aug 18;136:85-103. doi: 10.1016/j.ejmech.2017.04.072. Epub 2017 Apr 27. Eur J Med Chem. 2017. PMID: 28486210

6

Insights into the myosin II inhibitory potency of A-ring-modified (S)-blebbistatin analogs.

Verhasselt S, Stevens CV, Van den Broecke T, Bracke ME, Roman BI. Verhasselt S, et al. Among authors: bracke me. Bioorg Med Chem Lett. 2017 Jul 1;27(13):2986-2989. doi: 10.1016/j.bmcl.2017.05.008. Epub 2017 May 4. Bioorg Med Chem Lett. 2017. PMID: 28512027 Free article.

7

QSAR modeling of anti-invasive activity of organic compounds using structural descriptors.

Katritzky AR, Kuanar M, Dobchev DA, Vanhoecke BW, Karelson M, Parmar VS, Stevens CV, Bracke ME. Katritzky AR, et al. Among authors: bracke me. Bioorg Med Chem. 2006 Oct 15;14(20):6933-9. doi: 10.1016/j.bmc.2006.06.036. Bioorg Med Chem. 2006. PMID: 16908166

8

Exploration of the SAR of anti-invasive chalcones: synthesis and biological evaluation of conformationally restricted analogues.

Roman BI, Ryck TD, Dierickx L, Vanhoecke BW, Katritzky AR, Bracke M, Stevens CV. Roman BI, et al. Bioorg Med Chem. 2012 Aug 1;20(15):4812-9. doi: 10.1016/j.bmc.2012.05.069. Epub 2012 Jun 7. Bioorg Med Chem. 2012. PMID: 22743088

9

Assessment of the antineoplastic potential of chalcones in animal models.

Roman BI, Heugebaert TS, Bracke ME, Stevens CV. Roman BI, et al. Among authors: bracke me. Curr Med Chem. 2013;20(2):186-221. doi: 10.2174/092986713804806630. Curr Med Chem. 2013. PMID: 23244582 Review.

10

Chick heart invasion assay.

Bracke ME, Parmar VS, Depass AL, Stevens CV, Vanhoecke BW, Mareel MM. Bracke ME, et al. Methods Mol Biol. 2014;1070:93-106. doi: 10.1007/978-1-4614-8244-4_7. Methods Mol Biol. 2014. PMID: 24092434

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