Finke PE - Search Results

1

Inhibition of human leukocyte elastase. 1. Inhibition by C-7-substituted cephalosporin tert-butyl esters.

Doherty JB, Ashe BM, Barker PL, Blacklock TJ, Butcher JW, Chandler GO, Dahlgren ME, Davies P, Dorn CP Jr, Finke PE, et al. Doherty JB, et al. Among authors: finke pe. J Med Chem. 1990 Sep;33(9):2513-21. doi: 10.1021/jm00171a028. J Med Chem. 1990. PMID: 2391691

2

The discovery and biologic properties of cephalosporin-based inhibitors of PMN elastase.

Davies P, Ashe BM, Bonney RJ, Dorn C, Finke P, Fletcher D, Hanlon WA, Humes JL, Maycock A, Mumford RA, et al. Davies P, et al. Ann N Y Acad Sci. 1991;624:219-29. doi: 10.1111/j.1749-6632.1991.tb17021.x. Ann N Y Acad Sci. 1991. PMID: 2064223 Review. No abstract available.

3

Formation of polymorphonuclear leukocyte elastase: alpha 1 proteinase inhibitor complex and A alpha (1-21) fibrinopeptide in human blood stimulated with the calcium ionophore A23187. A model to characterize inhibitors of polymorphonuclear leukocyte elastase.

Pacholok SG, Davies P, Dorn C, Finke P, Hanlon WA, Mumford RA, Humes JL. Pacholok SG, et al. Biochem Pharmacol. 1995 May 17;49(10):1513-20. doi: 10.1016/0006-2952(95)00031-t. Biochem Pharmacol. 1995. PMID: 7763294

4

Inhibition of human leukocyte elastase. 4. Selection of a substituted cephalosporin (L-658,758) as a topical aerosol.

Finke PE, Shah SK, Ashe BM, Ball RG, Blacklock TJ, Bonney RJ, Brause KA, Chandler GO, Cotton M, Davies P, et al. Finke PE, et al. J Med Chem. 1992 Oct 16;35(21):3731-44. doi: 10.1021/jm00099a002. J Med Chem. 1992. PMID: 1433188

5

Orally active beta-lactam inhibitors of human leukocyte elastase-1. Activity of 3,3-diethyl-2-azetidinones.

Shah SK, Dorn CP Jr, Finke PE, Hale JJ, Hagmann WK, Brause KA, Chandler GO, Kissinger AL, Ashe BM, Weston H, et al. Shah SK, et al. Among authors: finke pe. J Med Chem. 1992 Oct 16;35(21):3745-54. doi: 10.1021/jm00099a003. J Med Chem. 1992. PMID: 1433189

6

Mechanism of inhibition of human leukocyte elastase by two cephalosporin derivatives.

Knight WB, Maycock AL, Green BG, Ashe BM, Gale P, Weston H, Finke PE, Hagmann WK, Shah SK, Doherty JB. Knight WB, et al. Among authors: finke pe. Biochemistry. 1992 Jun 2;31(21):4980-6. doi: 10.1021/bi00136a010. Biochemistry. 1992. PMID: 1599924

7

Inhibition of human leukocyte elastase. 2. Inhibition by substituted cephalosporin esters and amides.

Finke PE, Ashe BM, Knight WB, Maycock AL, Navia MA, Shah SK, Thompson KR, Underwood DJ, Weston H, Zimmerman M, et al. Finke PE, et al. J Med Chem. 1990 Sep;33(9):2522-8. doi: 10.1021/jm00171a029. J Med Chem. 1990. PMID: 2391692

8

Inhibition of human leukocyte elastase. 3. Synthesis and activity of 3'-substituted cephalosporins.

Shah SK, Brause KA, Chandler GO, Finke PE, Ashe BM, Weston H, Knight WB, Maycock AL, Doherty JB. Shah SK, et al. Among authors: finke pe. J Med Chem. 1990 Sep;33(9):2529-35. doi: 10.1021/jm00171a030. J Med Chem. 1990. PMID: 2391693

9

Orally active beta-lactam inhibitors of human leukocyte elastase. 3. Stereospecific synthesis and structure-activity relationships for 3,3-dialkylazetidin-2-ones.

Finke PE, Shah SK, Fletcher DS, Ashe BM, Brause KA, Chandler GO, Dellea PS, Hand KM, Maycock AL, Osinga DG, et al. Finke PE, et al. J Med Chem. 1995 Jun 23;38(13):2449-62. doi: 10.1021/jm00013a021. J Med Chem. 1995. PMID: 7608910

10

An inhibitor of leukocyte elastase prevents immune complex-mediated hemorrhage in the rat lung.

Fletcher DS, Osinga DG, Keenan K, Bonney RJ, Doherty JB, Finke PE, Shah SK, Davies P. Fletcher DS, et al. Among authors: finke pe. J Pharmacol Exp Ther. 1995 Jul;274(1):548-54. J Pharmacol Exp Ther. 1995. PMID: 7616444

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