Duong-Ly KC - Search Results

1

A highly selective dual insulin receptor (IR)/insulin-like growth factor 1 receptor (IGF-1R) inhibitor derived from an extracellular signal-regulated kinase (ERK) inhibitor.

Anastassiadis T, Duong-Ly KC, Deacon SW, Lafontant A, Ma H, Devarajan K, Dunbrack RL Jr, Wu J, Peterson JR. Anastassiadis T, et al. J Biol Chem. 2013 Sep 27;288(39):28068-77. doi: 10.1074/jbc.M113.505032. Epub 2013 Aug 9. J Biol Chem. 2013. PMID: 23935097 Free PMC article.

2

The human kinome and kinase inhibition.

Duong-Ly KC, Peterson JR. Duong-Ly KC, et al. Curr Protoc Pharmacol. 2013 Mar;Chapter 2:Unit2.9. doi: 10.1002/0471141755.ph0209s60. Curr Protoc Pharmacol. 2013. PMID: 23456613 Free PMC article.

3

Conformational analysis of the DFG-out kinase motif and biochemical profiling of structurally validated type II inhibitors.

Vijayan RS, He P, Modi V, Duong-Ly KC, Ma H, Peterson JR, Dunbrack RL Jr, Levy RM. Vijayan RS, et al. Among authors: duong ly kc. J Med Chem. 2015 Jan 8;58(1):466-79. doi: 10.1021/jm501603h. Epub 2014 Dec 12. J Med Chem. 2015. PMID: 25478866 Free PMC article.

4

A High-Throughput Radiometric Kinase Assay.

Duong-Ly KC, Peterson JR. Duong-Ly KC, et al. Methods Mol Biol. 2016;1360:87-95. doi: 10.1007/978-1-4939-3073-9_7. Methods Mol Biol. 2016. PMID: 26501904 Free PMC article.

5

Kinase Inhibitor Profiling Reveals Unexpected Opportunities to Inhibit Disease-Associated Mutant Kinases.

Duong-Ly KC, Devarajan K, Liang S, Horiuchi KY, Wang Y, Ma H, Peterson JR. Duong-Ly KC, et al. Cell Rep. 2016 Feb 2;14(4):772-781. doi: 10.1016/j.celrep.2015.12.080. Epub 2016 Jan 14. Cell Rep. 2016. PMID: 26776524 Free PMC article.

6

Reconstituted IMPDH polymers accommodate both catalytically active and inactive conformations.

Anthony SA, Burrell AL, Johnson MC, Duong-Ly KC, Kuo YM, Simonet JC, Michener P, Andrews A, Kollman JM, Peterson JR. Anthony SA, et al. Among authors: duong ly kc. Mol Biol Cell. 2017 Aug 9;28(20):2600-8. doi: 10.1091/mbc.E17-04-0263. Online ahead of print. Mol Biol Cell. 2017. PMID: 28794265 Free PMC article.

7

T cell activation triggers reversible inosine-5'-monophosphate dehydrogenase assembly.

Duong-Ly KC, Kuo YM, Johnson MC, Cote JM, Kollman JM, Soboloff J, Rall GF, Andrews AJ, Peterson JR. Duong-Ly KC, et al. J Cell Sci. 2018 Sep 5;131(17):jcs223289. doi: 10.1242/jcs.223289. J Cell Sci. 2018. PMID: 30154209 Free PMC article.

8

Capitalizing on tumor genotyping: towards the design of mutation specific inhibitors of phosphoinsitide-3-kinase.

Gabelli SB, Duong-Ly KC, Brower ET, Amzel LM. Gabelli SB, et al. Adv Enzyme Regul. 2011;51(1):273-9. doi: 10.1016/j.advenzreg.2010.09.013. Epub 2010 Oct 28. Adv Enzyme Regul. 2011. PMID: 21035489 Free PMC article. Review.

9

Structural and Enzymatic Characterization of a Nucleoside Diphosphate Sugar Hydrolase from Bdellovibrio bacteriovorus.

de la Peña AH, Suarez A, Duong-Ly KC, Schoeffield AJ, Pizarro-Dupuy MA, Zarr M, Pineiro SA, Amzel LM, Gabelli SB. de la Peña AH, et al. Among authors: duong ly kc. PLoS One. 2015 Nov 2;10(11):e0141716. doi: 10.1371/journal.pone.0141716. eCollection 2015. PLoS One. 2015. PMID: 26524597 Free PMC article.

10

The Nudix hydrolase CDP-chase, a CDP-choline pyrophosphatase, is an asymmetric dimer with two distinct enzymatic activities.

Duong-Ly KC, Gabelli SB, Xu W, Dunn CA, Schoeffield AJ, Bessman MJ, Amzel LM. Duong-Ly KC, et al. J Bacteriol. 2011 Jul;193(13):3175-85. doi: 10.1128/JB.00089-11. Epub 2011 Apr 29. J Bacteriol. 2011. PMID: 21531795 Free PMC article.

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