Gao LX - Search Results

1

The first synthesis of natural disulfide bruguiesulfurol and biological evaluation of its derivatives as a novel scaffold for PTP1B inhibitors.

Chen J, Jiang CS, Ma WQ, Gao LX, Gong JX, Li JY, Li J, Guo YW. Chen J, et al. Among authors: gao lx. Bioorg Med Chem Lett. 2013 Sep 15;23(18):5061-5. doi: 10.1016/j.bmcl.2013.07.039. Epub 2013 Jul 25. Bioorg Med Chem Lett. 2013. PMID: 23942421

2

Preparation of triazole-linked glycosylated α-ketocarboxylic acid derivatives as new PTP1B inhibitors.

Song Z, He XP, Li C, Gao LX, Wang ZX, Tang Y, Xie J, Li J, Chen GR. Song Z, et al. Among authors: gao lx. Carbohydr Res. 2011 Jan 3;346(1):140-5. doi: 10.1016/j.carres.2010.10.023. Epub 2010 Oct 30. Carbohydr Res. 2011. PMID: 21111404

3

A unique and rapid approach toward the efficient development of novel protein tyrosine phosphatase (PTP) inhibitors based on 'clicked' pseudo-glycopeptides.

Yang JW, He XP, Li C, Gao LX, Sheng L, Xie J, Shi XX, Tang Y, Li J, Chen GR. Yang JW, et al. Among authors: gao lx. Bioorg Med Chem Lett. 2011 Feb 15;21(4):1092-6. doi: 10.1016/j.bmcl.2010.12.126. Epub 2010 Dec 31. Bioorg Med Chem Lett. 2011. PMID: 21251827

4

Facile fabrication of promising protein tyrosine phosphatase (PTP) inhibitor entities based on 'clicked' serine/threonine-monosaccharide hybrids.

He XP, Deng Q, Gao LX, Li C, Zhang W, Zhou YB, Tang Y, Shi XX, Xie J, Li J, Chen GR, Chen K. He XP, et al. Among authors: gao lx. Bioorg Med Chem. 2011 Jul 1;19(13):3892-900. doi: 10.1016/j.bmc.2011.05.049. Epub 2011 May 27. Bioorg Med Chem. 2011. PMID: 21665482

5

Synthesis and biological evaluation of (±)-3-(2-(2-fluorobenzyloxy) naphthalen-6-yl)-2-aminopropanoic acid derivatives as novel PTP1B inhibitors.

Sun LP, Shen Q, Piao HH, Ma WP, Gao LX, Zhang W, Nan FJ, Li J, Piao HR. Sun LP, et al. Among authors: gao lx. Eur J Med Chem. 2011 Sep;46(9):3630-8. doi: 10.1016/j.ejmech.2011.05.027. Epub 2011 May 20. Eur J Med Chem. 2011. PMID: 21680062

6

Click to a focused library of benzyl 6-triazolo(hydroxy)benzoic glucosides: novel construction of PTP1B inhibitors on a sugar scaffold.

Li C, He XP, Zhang YJ, Li Z, Gao LX, Shi XX, Xie J, Li J, Chen GR, Tang Y. Li C, et al. Among authors: gao lx. Eur J Med Chem. 2011 Sep;46(9):4212-8. doi: 10.1016/j.ejmech.2011.06.025. Epub 2011 Jun 25. Eur J Med Chem. 2011. PMID: 21745700

7

Discovering the distinct inhibitory effects between C4-epimeric glycosyl amino acids: new insight into the development of protein tyrosine phosphatase inhibitors.

He XP, Li C, Wang ZZ, Gao LX, Shi XX, Tang Y, Xie J, Li J, Chen GR, Chen K. He XP, et al. Among authors: gao lx. Glycoconj J. 2011 Oct;28(7):493-7. doi: 10.1007/s10719-011-9347-0. Epub 2011 Sep 6. Glycoconj J. 2011. PMID: 21894463

8

A novel class of small-molecule caspase-3 inhibitors prepared by multicomponent reactions.

Zhu Q, Gao L, Chen Z, Zheng S, Shu H, Li J, Jiang H, Liu S. Zhu Q, et al. Eur J Med Chem. 2012 Aug;54:232-8. doi: 10.1016/j.ejmech.2012.05.001. Epub 2012 May 11. Eur J Med Chem. 2012. PMID: 22652225

9

Synthesis and biological evaluation of 2,4,6-trihydroxychalcone derivatives as novel protein tyrosine phosphatase 1B inhibitors.

Sun LP, Gao LX, Ma WP, Nan FJ, Li J, Piao HR. Sun LP, et al. Among authors: gao lx. Chem Biol Drug Des. 2012 Oct;80(4):584-90. doi: 10.1111/j.1747-0285.2012.01431.x. Epub 2012 Jul 13. Chem Biol Drug Des. 2012. PMID: 22805439

10

Synthesis and characterization of 5,7-dihydroxyflavanone derivatives as novel protein tyrosine phosphatase 1B inhibitors.

Sun LP, Ma WP, Gao LX, Yang LL, Quan YC, Li J, Piao HR. Sun LP, et al. Among authors: gao lx. J Enzyme Inhib Med Chem. 2013 Dec;28(6):1199-204. doi: 10.3109/14756366.2012.723206. Epub 2012 Sep 26. J Enzyme Inhib Med Chem. 2013. PMID: 23009604 Free article.

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