Howe SJ - Search Results

1

Targeted expression of human folylpolyglutamate synthase for selective enhancement of methotrexate chemotherapy in osteosarcoma cells.

Bienemann K, Staege MS, Howe SJ, Sena-Esteves M, Hanenberg H, Kramm CM. Bienemann K, et al. Among authors: howe sj. Cancer Gene Ther. 2013 Sep;20(9):514-20. doi: 10.1038/cgt.2013.48. Epub 2013 Aug 16. Cancer Gene Ther. 2013. PMID: 23949282

2

Cell-specific and efficient expression in mouse and human B cells by a novel hybrid immunoglobulin promoter in a lentiviral vector.

Laurie KL, Blundell MP, Baxendale HE, Howe SJ, Sinclair J, Qasim W, Brunsberg U, Thrasher AJ, Holmdahl R, Gustafsson K. Laurie KL, et al. Among authors: howe sj. Gene Ther. 2007 Dec;14(23):1623-31. doi: 10.1038/sj.gt.3303021. Epub 2007 Sep 13. Gene Ther. 2007. PMID: 17851547

3

Eliminating HIV-1 Packaging Sequences from Lentiviral Vector Proviruses Enhances Safety and Expedites Gene Transfer for Gene Therapy.

Vink CA, Counsell JR, Perocheau DP, Karda R, Buckley SMK, Brugman MH, Galla M, Schambach A, McKay TR, Waddington SN, Howe SJ. Vink CA, et al. Among authors: howe sj. Mol Ther. 2017 Aug 2;25(8):1790-1804. doi: 10.1016/j.ymthe.2017.04.028. Epub 2017 May 24. Mol Ther. 2017. PMID: 28550974 Free PMC article.

4

Lentiviral vector integration profiles differ in rodent postmitotic tissues.

Bartholomae CC, Arens A, Balaggan KS, Yáñez-Muñoz RJ, Montini E, Howe SJ, Paruzynski A, Korn B, Appelt JU, Macneil A, Cesana D, Abel U, Glimm H, Naldini L, Ali RR, Thrasher AJ, von Kalle C, Schmidt M. Bartholomae CC, et al. Among authors: howe sj. Mol Ther. 2011 Apr;19(4):703-10. doi: 10.1038/mt.2011.19. Epub 2011 Mar 1. Mol Ther. 2011. PMID: 21364536 Free PMC article.

5

Persistent episomal transgene expression in liver following delivery of a scaffold/matrix attachment region containing non-viral vector.

Argyros O, Wong SP, Niceta M, Waddington SN, Howe SJ, Coutelle C, Miller AD, Harbottle RP. Argyros O, et al. Among authors: howe sj. Gene Ther. 2008 Dec;15(24):1593-605. doi: 10.1038/gt.2008.113. Epub 2008 Jul 17. Gene Ther. 2008. PMID: 18633447

6

Correction of SCID-X1 using an enhancerless Vav promoter.

Almarza E, Zhang F, Santilli G, Blundell MP, Howe SJ, Thornhill SI, Bueren JA, Thrasher AJ. Almarza E, et al. Among authors: howe sj. Hum Gene Ther. 2011 Mar;22(3):263-70. doi: 10.1089/hum.2010.119. Epub 2011 Feb 7. Hum Gene Ther. 2011. PMID: 20887212

7

Efficient gene delivery to the adult and fetal CNS using pseudotyped non-integrating lentiviral vectors.

Rahim AA, Wong AM, Howe SJ, Buckley SM, Acosta-Saltos AD, Elston KE, Ward NJ, Philpott NJ, Cooper JD, Anderson PN, Waddington SN, Thrasher AJ, Raivich G. Rahim AA, et al. Among authors: howe sj. Gene Ther. 2009 Apr;16(4):509-20. doi: 10.1038/gt.2008.186. Epub 2009 Jan 22. Gene Ther. 2009. PMID: 19158847

8

Self-inactivating gammaretroviral vectors for gene therapy of X-linked severe combined immunodeficiency.

Thornhill SI, Schambach A, Howe SJ, Ulaganathan M, Grassman E, Williams D, Schiedlmeier B, Sebire NJ, Gaspar HB, Kinnon C, Baum C, Thrasher AJ. Thornhill SI, et al. Among authors: howe sj. Mol Ther. 2008 Mar;16(3):590-8. doi: 10.1038/sj.mt.6300393. Epub 2008 Jan 8. Mol Ther. 2008. PMID: 18180772 Free PMC article.

9

Lentiviral transduction of the murine lung provides efficient pseudotype and developmental stage-dependent cell-specific transgene expression.

Buckley SM, Howe SJ, Sheard V, Ward NJ, Coutelle C, Thrasher AJ, Waddington SN, McKay TR. Buckley SM, et al. Among authors: howe sj. Gene Ther. 2008 Aug;15(16):1167-75. doi: 10.1038/gt.2008.74. Epub 2008 Apr 24. Gene Ther. 2008. PMID: 18432275

10

Gene therapy progress and prospects: gene therapy for severe combined immunodeficiency.

Gaspar HB, Howe S, Thrasher AJ. Gaspar HB, et al. Gene Ther. 2003 Nov;10(24):1999-2004. doi: 10.1038/sj.gt.3302150. Gene Ther. 2003. PMID: 14566358 Review.

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