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Inhibition of the PI3K-AKT-MTORC1 axis reduces the burden of the m.3243A>G mtDNA mutation by promoting mitophagy and improving mitochondrial function.
Chung CY, Singh K, Sheshadri P, Valdebenito GE, Chacko AR, Costa Besada MA, Liang XF, Kabir L, Pitceathly RDS, Szabadkai G, Duchen MR. Chung CY, et al. Among authors: liang xf. Autophagy. 2024 Dec 12:1-16. doi: 10.1080/15548627.2024.2437908. Online ahead of print. Autophagy. 2024. PMID: 39667405 Free article.
298 results