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A novel biological role for the phospholipid lysophosphatidylinositol in nociceptive sensitization via activation of diverse G-protein signalling pathways in sensory nerves in vivo.
Gangadharan V, Selvaraj D, Kurejova M, Njoo C, Gritsch S, Škoricová D, Horstmann H, Offermanns S, Brown AJ, Kuner T, Tappe-Theodor A, Kuner R. Gangadharan V, et al. Pain. 2013 Dec;154(12):2801-2812. doi: 10.1016/j.pain.2013.08.019. Epub 2013 Aug 22. Pain. 2013. PMID: 23973358
Peripheral calcium-permeable AMPA receptors regulate chronic inflammatory pain in mice.
Gangadharan V, Wang R, Ulzhöfer B, Luo C, Bardoni R, Bali KK, Agarwal N, Tegeder I, Hildebrandt U, Nagy GG, Todd AJ, Ghirri A, Häussler A, Sprengel R, Seeburg PH, MacDermott AB, Lewin GR, Kuner R. Gangadharan V, et al. J Clin Invest. 2011 Apr;121(4):1608-23. doi: 10.1172/JCI44911. Epub 2011 Mar 7. J Clin Invest. 2011. PMID: 21383497 Free PMC article.
Presynaptically localized cyclic GMP-dependent protein kinase 1 is a key determinant of spinal synaptic potentiation and pain hypersensitivity.
Luo C, Gangadharan V, Bali KK, Xie RG, Agarwal N, Kurejova M, Tappe-Theodor A, Tegeder I, Feil S, Lewin G, Polgar E, Todd AJ, Schlossmann J, Hofmann F, Liu DL, Hu SJ, Feil R, Kuner T, Kuner R. Luo C, et al. Among authors: gangadharan v. PLoS Biol. 2012;10(3):e1001283. doi: 10.1371/journal.pbio.1001283. Epub 2012 Mar 13. PLoS Biol. 2012. PMID: 22427743 Free PMC article.
Pain hypersensitivity mechanisms at a glance.
Gangadharan V, Kuner R. Gangadharan V, et al. Dis Model Mech. 2013 Jul;6(4):889-95. doi: 10.1242/dmm.011502. Dis Model Mech. 2013. PMID: 23828645 Free PMC article. Review.
A Functional Role for VEGFR1 Expressed in Peripheral Sensory Neurons in Cancer Pain.
Selvaraj D, Gangadharan V, Michalski CW, Kurejova M, Stösser S, Srivastava K, Schweizerhof M, Waltenberger J, Ferrara N, Heppenstall P, Shibuya M, Augustin HG, Kuner R. Selvaraj D, et al. Among authors: gangadharan v. Cancer Cell. 2015 Jun 8;27(6):780-96. doi: 10.1016/j.ccell.2015.04.017. Cancer Cell. 2015. PMID: 26058077 Free PMC article.
97 results