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Bcl10 controls TCR- and FcgammaR-induced actin polymerization.
Rueda D, Gaide O, Ho L, Lewkowicz E, Niedergang F, Hailfinger S, Rebeaud F, Guzzardi M, Conne B, Thelen M, Delon J, Ferch U, Mak TW, Ruland J, Schwaller J, Thome M. Rueda D, et al. Among authors: thome m. J Immunol. 2007 Apr 1;178(7):4373-84. doi: 10.4049/jimmunol.178.7.4373. J Immunol. 2007. PMID: 17371994
The proteolytic activity of the paracaspase MALT1 is key in T cell activation.
Rebeaud F, Hailfinger S, Posevitz-Fejfar A, Tapernoux M, Moser R, Rueda D, Gaide O, Guzzardi M, Iancu EM, Rufer N, Fasel N, Thome M. Rebeaud F, et al. Among authors: thome m. Nat Immunol. 2008 Mar;9(3):272-81. doi: 10.1038/ni1568. Epub 2008 Feb 10. Nat Immunol. 2008. PMID: 18264101
Evidence for a TCR affinity threshold delimiting maximal CD8 T cell function.
Schmid DA, Irving MB, Posevitz V, Hebeisen M, Posevitz-Fejfar A, Sarria JC, Gomez-Eerland R, Thome M, Schumacher TN, Romero P, Speiser DE, Zoete V, Michielin O, Rufer N. Schmid DA, et al. Among authors: thome m. J Immunol. 2010 May 1;184(9):4936-46. doi: 10.4049/jimmunol.1000173. Epub 2010 Mar 29. J Immunol. 2010. PMID: 20351194
Antigen receptor signaling to NF-kappaB via CARMA1, BCL10, and MALT1.
Thome M, Charton JE, Pelzer C, Hailfinger S. Thome M, et al. Cold Spring Harb Perspect Biol. 2010 Sep;2(9):a003004. doi: 10.1101/cshperspect.a003004. Epub 2010 Aug 4. Cold Spring Harb Perspect Biol. 2010. PMID: 20685844 Free PMC article. Review.
IKKα takes control of canonical NF-κB activation.
Pelzer C, Thome M. Pelzer C, et al. Among authors: thome m. Nat Immunol. 2011 Aug 18;12(9):815-6. doi: 10.1038/ni.2082. Nat Immunol. 2011. PMID: 21852778 No abstract available.
188 results