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DNA targeting specificity of RNA-guided Cas9 nucleases.
Hsu PD, Scott DA, Weinstein JA, Ran FA, Konermann S, Agarwala V, Li Y, Fine EJ, Wu X, Shalem O, Cradick TJ, Marraffini LA, Bao G, Zhang F. Hsu PD, et al. Among authors: scott da. Nat Biotechnol. 2013 Sep;31(9):827-32. doi: 10.1038/nbt.2647. Epub 2013 Jul 21. Nat Biotechnol. 2013. PMID: 23873081 Free PMC article.
Optical control of mammalian endogenous transcription and epigenetic states.
Konermann S, Brigham MD, Trevino A, Hsu PD, Heidenreich M, Cong L, Platt RJ, Scott DA, Church GM, Zhang F. Konermann S, et al. Among authors: scott da. Nature. 2013 Aug 22;500(7463):472-476. doi: 10.1038/nature12466. Epub 2013 Aug 23. Nature. 2013. PMID: 23877069 Free PMC article.
Genome engineering using the CRISPR-Cas9 system.
Ran FA, Hsu PD, Wright J, Agarwala V, Scott DA, Zhang F. Ran FA, et al. Among authors: scott da. Nat Protoc. 2013 Nov;8(11):2281-2308. doi: 10.1038/nprot.2013.143. Epub 2013 Oct 24. Nat Protoc. 2013. PMID: 24157548 Free PMC article.
Genome-scale CRISPR-Cas9 knockout screening in human cells.
Shalem O, Sanjana NE, Hartenian E, Shi X, Scott DA, Mikkelson T, Heckl D, Ebert BL, Root DE, Doench JG, Zhang F. Shalem O, et al. Among authors: scott da. Science. 2014 Jan 3;343(6166):84-87. doi: 10.1126/science.1247005. Epub 2013 Dec 12. Science. 2014. PMID: 24336571 Free PMC article.
Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells.
Wu X, Scott DA, Kriz AJ, Chiu AC, Hsu PD, Dadon DB, Cheng AW, Trevino AE, Konermann S, Chen S, Jaenisch R, Zhang F, Sharp PA. Wu X, et al. Among authors: scott da. Nat Biotechnol. 2014 Jul;32(7):670-6. doi: 10.1038/nbt.2889. Epub 2014 Apr 20. Nat Biotechnol. 2014. PMID: 24752079 Free PMC article.
Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis.
Chen S, Sanjana NE, Zheng K, Shalem O, Lee K, Shi X, Scott DA, Song J, Pan JQ, Weissleder R, Lee H, Zhang F, Sharp PA. Chen S, et al. Among authors: scott da. Cell. 2015 Mar 12;160(6):1246-60. doi: 10.1016/j.cell.2015.02.038. Epub 2015 Mar 5. Cell. 2015. PMID: 25748654 Free PMC article.
In vivo genome editing using Staphylococcus aureus Cas9.
Ran FA, Cong L, Yan WX, Scott DA, Gootenberg JS, Kriz AJ, Zetsche B, Shalem O, Wu X, Makarova KS, Koonin EV, Sharp PA, Zhang F. Ran FA, et al. Among authors: scott da. Nature. 2015 Apr 9;520(7546):186-91. doi: 10.1038/nature14299. Epub 2015 Apr 1. Nature. 2015. PMID: 25830891 Free PMC article.
Rationally engineered Cas9 nucleases with improved specificity.
Slaymaker IM, Gao L, Zetsche B, Scott DA, Yan WX, Zhang F. Slaymaker IM, et al. Among authors: scott da. Science. 2016 Jan 1;351(6268):84-8. doi: 10.1126/science.aad5227. Epub 2015 Dec 1. Science. 2016. PMID: 26628643 Free PMC article.
910 results