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Mesenchymal differentiation mediated by NF-κB promotes radiation resistance in glioblastoma.
Bhat KPL, Balasubramaniyan V, Vaillant B, Ezhilarasan R, Hummelink K, Hollingsworth F, Wani K, Heathcock L, James JD, Goodman LD, Conroy S, Long L, Lelic N, Wang S, Gumin J, Raj D, Kodama Y, Raghunathan A, Olar A, Joshi K, Pelloski CE, Heimberger A, Kim SH, Cahill DP, Rao G, Den Dunnen WFA, Boddeke HWGM, Phillips HS, Nakano I, Lang FF, Colman H, Sulman EP, Aldape K. Bhat KPL, et al. Among authors: joshi k. Cancer Cell. 2013 Sep 9;24(3):331-46. doi: 10.1016/j.ccr.2013.08.001. Epub 2013 Aug 29. Cancer Cell. 2013. PMID: 23993863 Free PMC article.
Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway.
Nakano I, Joshi K, Visnyei K, Hu B, Watanabe M, Lam D, Wexler E, Saigusa K, Nakamura Y, Laks DR, Mischel PS, Viapiano M, Kornblum HI. Nakano I, et al. Among authors: joshi k. Neuro Oncol. 2011 Jun;13(6):622-34. doi: 10.1093/neuonc/nor023. Epub 2011 May 9. Neuro Oncol. 2011. PMID: 21558073 Free PMC article.
Telomestatin impairs glioma stem cell survival and growth through the disruption of telomeric G-quadruplex and inhibition of the proto-oncogene, c-Myb.
Miyazaki T, Pan Y, Joshi K, Purohit D, Hu B, Demir H, Mazumder S, Okabe S, Yamori T, Viapiano M, Shin-ya K, Seimiya H, Nakano I. Miyazaki T, et al. Among authors: joshi k. Clin Cancer Res. 2012 Mar 1;18(5):1268-80. doi: 10.1158/1078-0432.CCR-11-1795. Epub 2012 Jan 9. Clin Cancer Res. 2012. PMID: 22230766 Free PMC article.
Impairment of glioma stem cell survival and growth by a novel inhibitor for Survivin-Ran protein complex.
Guvenc H, Pavlyukov MS, Joshi K, Kurt H, Banasavadi-Siddegowda YK, Mao P, Hong C, Yamada R, Kwon CH, Bhasin D, Chettiar S, Kitange G, Park IH, Sarkaria JN, Li C, Shakhparonov MI, Nakano I. Guvenc H, et al. Among authors: joshi k. Clin Cancer Res. 2013 Feb 1;19(3):631-42. doi: 10.1158/1078-0432.CCR-12-0647. Epub 2012 Dec 18. Clin Cancer Res. 2013. PMID: 23251006 Free PMC article.
Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3.
Mao P, Joshi K, Li J, Kim SH, Li P, Santana-Santos L, Luthra S, Chandran UR, Benos PV, Smith L, Wang M, Hu B, Cheng SY, Sobol RW, Nakano I. Mao P, et al. Among authors: joshi k. Proc Natl Acad Sci U S A. 2013 May 21;110(21):8644-9. doi: 10.1073/pnas.1221478110. Epub 2013 May 6. Proc Natl Acad Sci U S A. 2013. PMID: 23650391 Free PMC article. Clinical Trial.
3,090 results