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A small-molecule inhibitor of BCL6 kills DLBCL cells in vitro and in vivo.
Cerchietti LC, Ghetu AF, Zhu X, Da Silva GF, Zhong S, Matthews M, Bunting KL, Polo JM, Farès C, Arrowsmith CH, Yang SN, Garcia M, Coop A, Mackerell AD Jr, Privé GG, Melnick A. Cerchietti LC, et al. Among authors: melnick a. Cancer Cell. 2010 Apr 13;17(4):400-11. doi: 10.1016/j.ccr.2009.12.050. Cancer Cell. 2010. PMID: 20385364 Free PMC article.
Epigenetics and B-cell lymphoma.
Shaknovich R, Melnick A. Shaknovich R, et al. Among authors: melnick a. Curr Opin Hematol. 2011 Jul;18(4):293-9. doi: 10.1097/MOH.0b013e32834788cf. Curr Opin Hematol. 2011. PMID: 21577103 Free PMC article. Review.
SYK inhibition and response prediction in diffuse large B-cell lymphoma.
Cheng S, Coffey G, Zhang XH, Shaknovich R, Song Z, Lu P, Pandey A, Melnick AM, Sinha U, Wang YL. Cheng S, et al. Among authors: melnick am. Blood. 2011 Dec 8;118(24):6342-52. doi: 10.1182/blood-2011-02-333773. Epub 2011 Oct 24. Blood. 2011. PMID: 22025527 Free article.
MALT1 small molecule inhibitors specifically suppress ABC-DLBCL in vitro and in vivo.
Fontan L, Yang C, Kabaleeswaran V, Volpon L, Osborne MJ, Beltran E, Garcia M, Cerchietti L, Shaknovich R, Yang SN, Fang F, Gascoyne RD, Martinez-Climent JA, Glickman JF, Borden K, Wu H, Melnick A. Fontan L, et al. Among authors: melnick a. Cancer Cell. 2012 Dec 11;22(6):812-24. doi: 10.1016/j.ccr.2012.11.003. Cancer Cell. 2012. PMID: 23238016 Free PMC article.
Targeting lymphomas through MALT1 inhibition.
Fontan L, Melnick A. Fontan L, et al. Among authors: melnick a. Oncotarget. 2012 Dec;3(12):1493-4. doi: 10.18632/oncotarget.819. Oncotarget. 2012. PMID: 23455603 Free PMC article. No abstract available.
Downregulation of FOXP1 is required during germinal center B-cell function.
Sagardoy A, Martinez-Ferrandis JI, Roa S, Bunting KL, Aznar MA, Elemento O, Shaknovich R, Fontán L, Fresquet V, Perez-Roger I, Robles EF, De Smedt L, Sagaert X, Melnick A, Martinez-Climent JA. Sagardoy A, et al. Among authors: melnick a. Blood. 2013 May 23;121(21):4311-20. doi: 10.1182/blood-2012-10-462846. Epub 2013 Apr 11. Blood. 2013. PMID: 23580662 Free PMC article.
464 results