de Waart DR - Search Results

1

Polyinosinic acid blocks adeno-associated virus macrophage endocytosis in vitro and enhances adeno-associated virus liver-directed gene therapy in vivo.

van Dijk R, Montenegro-Miranda PS, Riviere C, Schilderink R, ten Bloemendaal L, van Gorp J, Duijst S, de Waart DR, Beuers U, Haisma HJ, Bosma PJ. van Dijk R, et al. Among authors: de waart dr. Hum Gene Ther. 2013 Sep;24(9):807-13. doi: 10.1089/hum.2013.086. Hum Gene Ther. 2013. PMID: 24010701

2

Mycophenolate mofetil impairs transduction of single-stranded adeno-associated viral vectors.

Montenegro-Miranda PS, ten Bloemendaal L, Kunne C, de Waart DR, Bosma PJ. Montenegro-Miranda PS, et al. Among authors: de waart dr. Hum Gene Ther. 2011 May;22(5):605-12. doi: 10.1089/hum.2010.222. Epub 2011 Apr 11. Hum Gene Ther. 2011. PMID: 21222531

3

Oral availability of cefadroxil depends on ABCC3 and ABCC4.

de Waart DR, van de Wetering K, Kunne C, Duijst S, Paulusma CC, Oude Elferink RP. de Waart DR, et al. Drug Metab Dispos. 2012 Mar;40(3):515-21. doi: 10.1124/dmd.111.041731. Epub 2011 Dec 13. Drug Metab Dispos. 2012. PMID: 22166395

4

Overexpression of insulin like growth factor binding protein 5 reduces liver fibrosis in chronic cholangiopathy.

Sokolović A, Montenegro-Miranda PS, de Waart DR, Cappai RM, Duijst S, Sokolović M, Bosma PJ. Sokolović A, et al. Among authors: de waart dr. Biochim Biophys Acta. 2012 Jun;1822(6):996-1003. doi: 10.1016/j.bbadis.2012.02.022. Epub 2012 Mar 13. Biochim Biophys Acta. 2012. PMID: 22434064 Free article.

5

Ezetimibe: A biomarker for efficacy of liver directed UGT1A1 gene therapy for inherited hyperbilirubinemia.

Montenegro-Miranda PS, Sneitz N, de Waart DR, Ten Bloemendaal L, Duijst S, de Knegt RJ, Beuers U, Finel M, Bosma PJ. Montenegro-Miranda PS, et al. Among authors: de waart dr, de knegt rj. Biochim Biophys Acta. 2012 Aug;1822(8):1223-9. doi: 10.1016/j.bbadis.2012.04.013. Epub 2012 Apr 21. Biochim Biophys Acta. 2012. PMID: 22546842 Free article.

6

Defective bile salt biosynthesis and hydroxylation in mice with reduced cytochrome P450 activity.

Kunne C, Acco A, Hohenester S, Duijst S, de Waart DR, Zamanbin A, Oude Elferink RP. Kunne C, et al. Among authors: de waart dr. Hepatology. 2013 Apr;57(4):1509-17. doi: 10.1002/hep.26133. Epub 2013 Jan 18. Hepatology. 2013. PMID: 23184615

7

In the rat liver, Adenoviral gene transfer efficiency is comparable to AAV.

Montenegro-Miranda PS, Pichard V, Aubert D, Ten Bloemendaal L, Duijst S, de Waart DR, Ferry N, Bosma PJ. Montenegro-Miranda PS, et al. Among authors: de waart dr. Gene Ther. 2014 Feb;21(2):168-74. doi: 10.1038/gt.2013.69. Epub 2013 Nov 28. Gene Ther. 2014. PMID: 24285217

8

Adeno-associated viral vector serotype 5 poorly transduces liver in rat models.

Montenegro-Miranda PS, Pañeda A, ten Bloemendaal L, Duijst S, de Waart DR, Gonzalez- Aseguinolaza G, Bosma PJ. Montenegro-Miranda PS, et al. Among authors: de waart dr. PLoS One. 2013 Dec 27;8(12):e82597. doi: 10.1371/journal.pone.0082597. eCollection 2013. PLoS One. 2013. PMID: 24386104 Free PMC article.

9

FXR-dependent reduction of hepatic steatosis in a bile salt deficient mouse model.

Kunne C, Acco A, Duijst S, de Waart DR, Paulusma CC, Gaemers I, Oude Elferink RP. Kunne C, et al. Among authors: de waart dr. Biochim Biophys Acta. 2014 May;1842(5):739-46. doi: 10.1016/j.bbadis.2014.02.004. Epub 2014 Feb 15. Biochim Biophys Acta. 2014. PMID: 24548803 Free article.

10

Hepatic cytochrome P450 deficiency in mouse models for intrahepatic cholestasis predispose to bile salt-induced cholestasis.

Kunne C, de Graaff M, Duijst S, de Waart DR, Oude Elferink RP, Paulusma CC. Kunne C, et al. Among authors: de waart dr, de graaff m. Lab Invest. 2014 Oct;94(10):1103-13. doi: 10.1038/labinvest.2014.102. Epub 2014 Jul 28. Lab Invest. 2014. PMID: 25068656 Free article.

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