Parker RA - Search Results

1

Selective inhibition of cholesterol synthesis in liver versus extrahepatic tissues by HMG-CoA reductase inhibitors.

Parker RA, Clark RW, Sit SY, Lanier TL, Grosso RA, Wright JJ. Parker RA, et al. J Lipid Res. 1990 Jul;31(7):1271-82. J Lipid Res. 1990. PMID: 2401858 Free article.

2

Hypocholesterolemic activity of synthetic and natural tocotrienols.

Pearce BC, Parker RA, Deason ME, Qureshi AA, Wright JJ. Pearce BC, et al. Among authors: parker ra. J Med Chem. 1992 Oct 2;35(20):3595-606. doi: 10.1021/jm00098a002. J Med Chem. 1992. PMID: 1433170

3

Synthesis, biological profile, and quantitative structure-activity relationship of a series of novel 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors.

Sit SY, Parker RA, Motoc I, Han W, Balasubramanian N, Catt JD, Brown PJ, Harte WE, Thompson MD, Wright JJ. Sit SY, et al. Among authors: parker ra. J Med Chem. 1990 Nov;33(11):2982-99. doi: 10.1021/jm00173a013. J Med Chem. 1990. PMID: 2231596

4

A potent, tissue-selective, synthetic inhibitor of HMG-CoA reductase.

Balasubramanian N, Brown PJ, Catt JD, Han WT, Parker RA, Sit SY, Wright JJ. Balasubramanian N, et al. Among authors: parker ra. J Med Chem. 1989 Sep;32(9):2038-41. doi: 10.1021/jm00129a004. J Med Chem. 1989. PMID: 2769677 No abstract available.

5

Inhibitors of cholesterol biosynthesis. 2. Hypocholesterolemic and antioxidant activities of benzopyran and tetrahydronaphthalene analogues of the tocotrienols.

Pearce BC, Parker RA, Deason ME, Dischino DD, Gillespie E, Qureshi AA, Volk K, Wright JJ. Pearce BC, et al. Among authors: parker ra. J Med Chem. 1994 Feb 18;37(4):526-41. doi: 10.1021/jm00030a012. J Med Chem. 1994. PMID: 8120870

6

Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.

Parker RA, Pearce BC, Clark RW, Gordon DA, Wright JJ. Parker RA, et al. J Biol Chem. 1993 May 25;268(15):11230-8. J Biol Chem. 1993. PMID: 8388388 Free article.

7

Phosphorylation and degradation of HMG CoA reductase.

Miller SJ, Parker RA, Gibson DM. Miller SJ, et al. Among authors: parker ra. Adv Enzyme Regul. 1989;28:65-77. doi: 10.1016/0065-2571(89)90064-2. Adv Enzyme Regul. 1989. PMID: 2624176

8

Phosphorylation state of HMG CoA reductase affects its catalytic activity and degradation.

Parker RA, Miller SJ, Gibson DM. Parker RA, et al. Adv Enzyme Regul. 1986;25:329-43. doi: 10.1016/0065-2571(86)90022-1. Adv Enzyme Regul. 1986. PMID: 3028050

9

Phosphorylation of microsomal HMG CoA reductase increases susceptibility to proteolytic degradation in vitro.

Parker RA, Miller SJ, Gibson DM. Parker RA, et al. Biochem Biophys Res Commun. 1984 Dec 14;125(2):629-35. doi: 10.1016/0006-291x(84)90585-0. Biochem Biophys Res Commun. 1984. PMID: 6097245

10

Modulation of hydroxymethylglutaryl-CoA reductase activity, reductase kinase activity, and cholesterol synthesis in rat hepatocytes in response to insulin and glucagon.

Ingebritsen TS, Geelen MJ, Parker RA, Evenson KJ, Gibson DM. Ingebritsen TS, et al. Among authors: parker ra. J Biol Chem. 1979 Oct 25;254(20):9986-9. J Biol Chem. 1979. PMID: 489617 Free article. No abstract available.

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