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CR1-mediated ATP release by human red blood cells promotes CR1 clustering and modulates the immune transfer process.
Melhorn MI, Brodsky AS, Estanislau J, Khoory JA, Illigens B, Hamachi I, Kurishita Y, Fraser AD, Nicholson-Weller A, Dolmatova E, Duffy HS, Ghiran IC. Melhorn MI, et al. Among authors: brodsky as. J Biol Chem. 2013 Oct 25;288(43):31139-53. doi: 10.1074/jbc.M113.486035. Epub 2013 Sep 10. J Biol Chem. 2013. PMID: 24022490 Free PMC article. Clinical Trial.
Aberrant expression of collagen type X in solid tumor stroma is associated with EMT, immunosuppressive and pro-metastatic pathways, bone marrow stromal cell signatures, and poor survival prognosis.
Famili-Youth EHH, Famili-Youth A, Yang D, Siddique A, Wu EY, Liu W, Resnick MB, Chen Q, Brodsky AS. Famili-Youth EHH, et al. Among authors: brodsky as. bioRxiv [Preprint]. 2024 Nov 14:2024.11.13.621984. doi: 10.1101/2024.11.13.621984. bioRxiv. 2024. PMID: 39605631 Free PMC article. Preprint.
The plasma miRNAome in ADNI: Signatures to aid the detection of at-risk individuals.
Krüger DM, Pena-Centeno T, Liu S, Park T, Kaurani L, Pradhan R, Huang YN, Risacher SL, Burkhardt S, Schütz AL, Wan Y, Shaw LM, Brodsky AS, DeStefano AL, Lin H, Schroeder R, Krunic A, Hempel N, Sananbenesi F, Blusztajn JK, Saykin AJ, Delalle I, Nho K, Fischer A; Alzheimer's Disease Neuroimaging Initiative. Krüger DM, et al. Among authors: brodsky as. Alzheimers Dement. 2024 Nov;20(11):7479-7494. doi: 10.1002/alz.14157. Epub 2024 Sep 18. Alzheimers Dement. 2024. PMID: 39291752 Free PMC article.
Plasma miRNAs across the Alzheimer's disease continuum: Relationship to central biomarkers.
Liu S, Park T, Krüger DM, Pena-Centeno T, Burkhardt S, Schutz AL, Huang YN, Rosewood T, Chaudhuri S, Cho M, Risacher SL, Wan Y, Shaw LM, Sananbenesi F, Brodsky AS, Lin H, Krunic A, Blusztajn JK, Saykin AJ, Delalle I, Fischer A, Nho K; Alzheimer's Disease Neuroimaging Initiative. Liu S, et al. Among authors: brodsky as. Alzheimers Dement. 2024 Nov;20(11):7698-7714. doi: 10.1002/alz.14230. Epub 2024 Sep 18. Alzheimers Dement. 2024. PMID: 39291737 Free PMC article.
Modulation of blood-tumor barrier transcriptional programs improves intra-tumoral drug delivery and potentiates chemotherapy in GBM.
Jimenez-Macias JL, Vaughn-Beaucaire P, Bharati A, Xu Z, Forrest M, Hong J, Sun M, Schmidt A, Clark J, Hawkins W, Mercado N, Real J, Huntington K, Zdioruk M, Nowicki MO, Cho CF, Wu B, Li W, Logan T, Manz KE, Pennell KD, Fedeles BI, Brodsky AS, Lawler SE. Jimenez-Macias JL, et al. Among authors: brodsky as. bioRxiv [Preprint]. 2024 Aug 28:2024.08.26.609797. doi: 10.1101/2024.08.26.609797. bioRxiv. 2024. PMID: 39253453 Free PMC article. Preprint.
FOXO3 regulates a common genomic program in aging and glioblastoma stem cells.
Audesse AJ, Karashchuk G, Gardell ZA, Lakis NS, Maybury-Lewis SY, Brown AK, Leeman DS, Teo YV, Neretti N, Anthony DC, Brodsky AS, Webb AE. Audesse AJ, et al. Among authors: brodsky as. Aging Cancer. 2021 Dec;2(4):137-159. doi: 10.1002/aac2.12043. Epub 2021 Dec 18. Aging Cancer. 2021. PMID: 36303712 Free PMC article.
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