Marcu KB - Search Results

1

IKKα/CHUK regulates extracellular matrix remodeling independent of its kinase activity to facilitate articular chondrocyte differentiation.

Olivotto E, Otero M, Astolfi A, Platano D, Facchini A, Pagani S, Flamigni F, Facchini A, Goldring MB, Borzì RM, Marcu KB. Olivotto E, et al. Among authors: marcu kb. PLoS One. 2013 Sep 2;8(9):e73024. doi: 10.1371/journal.pone.0073024. eCollection 2013. PLoS One. 2013. PMID: 24023802 Free PMC article.

2

Differential requirements for IKKalpha and IKKbeta in the differentiation of primary human osteoarthritic chondrocytes.

Olivotto E, Borzi RM, Vitellozzi R, Pagani S, Facchini A, Battistelli M, Penzo M, Li X, Flamigni F, Li J, Falcieri E, Facchini A, Marcu KB. Olivotto E, et al. Among authors: marcu kb. Arthritis Rheum. 2008 Jan;58(1):227-39. doi: 10.1002/art.23211. Arthritis Rheum. 2008. PMID: 18163512 Free PMC article.

3

Matrix metalloproteinase 13 loss associated with impaired extracellular matrix remodeling disrupts chondrocyte differentiation by concerted effects on multiple regulatory factors.

Borzí RM, Olivotto E, Pagani S, Vitellozzi R, Neri S, Battistelli M, Falcieri E, Facchini A, Flamigni F, Penzo M, Platano D, Santi S, Facchini A, Marcu KB. Borzí RM, et al. Among authors: marcu kb. Arthritis Rheum. 2010 Aug;62(8):2370-81. doi: 10.1002/art.27512. Arthritis Rheum. 2010. PMID: 20506238 Free PMC article.

4

Pathophysiology of osteoarthritis: canonical NF-κB/IKKβ-dependent and kinase-independent effects of IKKα in cartilage degradation and chondrocyte differentiation.

Olivotto E, Otero M, Marcu KB, Goldring MB. Olivotto E, et al. Among authors: marcu kb. RMD Open. 2015 Aug 15;1(Suppl 1):e000061. doi: 10.1136/rmdopen-2015-000061. eCollection 2015. RMD Open. 2015. PMID: 26557379 Free PMC article. Review.

5

NF-kappaB signaling: multiple angles to target OA.

Marcu KB, Otero M, Olivotto E, Borzi RM, Goldring MB. Marcu KB, et al. Curr Drug Targets. 2010 May;11(5):599-613. doi: 10.2174/138945010791011938. Curr Drug Targets. 2010. PMID: 20199390 Free PMC article. Review.

6

Roles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis.

Goldring MB, Otero M, Plumb DA, Dragomir C, Favero M, El Hachem K, Hashimoto K, Roach HI, Olivotto E, Borzì RM, Marcu KB. Goldring MB, et al. Among authors: marcu kb. Eur Cell Mater. 2011 Feb 24;21:202-20. doi: 10.22203/ecm.v021a16. Eur Cell Mater. 2011. PMID: 21351054 Free PMC article.

7

Basal and IL-1β enhanced chondrocyte chemotactic activity on monocytes are co-dependent on both IKKα and IKKβ NF-κB activating kinases.

Olivotto E, Minguzzi M, D'Adamo S, Astolfi A, Santi S, Uguccioni M, Marcu KB, Borzì RM. Olivotto E, et al. Among authors: marcu kb. Sci Rep. 2021 Nov 4;11(1):21697. doi: 10.1038/s41598-021-01063-2. Sci Rep. 2021. PMID: 34737366 Free PMC article.

8

Chemokines in cartilage degradation.

Borzì RM, Mazzetti I, Marcu KB, Facchini A. Borzì RM, et al. Among authors: marcu kb. Clin Orthop Relat Res. 2004 Oct;(427 Suppl):S53-61. doi: 10.1097/01.blo.0000143805.64755.4f. Clin Orthop Relat Res. 2004. PMID: 15480075 Review.

9

Polyamine depletion inhibits NF-kappaB binding to DNA and interleukin-8 production in human chondrocytes stimulated by tumor necrosis factor-alpha.

Facchini A, Borzí RM, Marcu KB, Stefanelli C, Olivotto E, Goldring MB, Facchini A, Flamigni F. Facchini A, et al. Among authors: marcu kb. J Cell Physiol. 2005 Sep;204(3):956-63. doi: 10.1002/jcp.20368. J Cell Physiol. 2005. PMID: 15828019 Free PMC article.

10

Sustained NF-kappaB activation produces a short-term cell proliferation block in conjunction with repressing effectors of cell cycle progression controlled by E2F or FoxM1.

Penzo M, Massa PE, Olivotto E, Bianchi F, Borzi RM, Hanidu A, Li X, Li J, Marcu KB. Penzo M, et al. Among authors: marcu kb. J Cell Physiol. 2009 Jan;218(1):215-27. doi: 10.1002/jcp.21596. J Cell Physiol. 2009. PMID: 18803232 Free PMC article.

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