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Potent triazolyl-proline-based inhibitors of HCV NS3 protease.
Naud J, Lemke C, Goudreau N, Beaulieu E, White PD, Llinàs-Brunet M, Forgione P. Naud J, et al. Among authors: forgione p. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3400-4. doi: 10.1016/j.bmcl.2008.04.012. Epub 2008 Apr 10. Bioorg Med Chem Lett. 2008. PMID: 18448339
Discovery of a potent and selective noncovalent linear inhibitor of the hepatitis C virus NS3 protease (BI 201335).
Llinàs-Brunet M, Bailey MD, Goudreau N, Bhardwaj PK, Bordeleau J, Bös M, Bousquet Y, Cordingley MG, Duan J, Forgione P, Garneau M, Ghiro E, Gorys V, Goulet S, Halmos T, Kawai SH, Naud J, Poupart MA, White PW. Llinàs-Brunet M, et al. Among authors: forgione p. J Med Chem. 2010 Sep 9;53(17):6466-76. doi: 10.1021/jm100690x. J Med Chem. 2010. PMID: 20715823
Synthesis and optimization of a novel series of HCV NS3 protease inhibitors: 4-arylproline analogs.
Bilodeau F, Bailey MD, Bhardwaj PK, Bordeleau J, Forgione P, Garneau M, Ghiro E, Gorys V, Halmos T, Jolicoeur ES, Leblanc M, Lemke CT, Naud J, O'Meara J, White PW, Llinàs-Brunet M. Bilodeau F, et al. Among authors: forgione p. Bioorg Med Chem Lett. 2013 Jul 15;23(14):4267-71. doi: 10.1016/j.bmcl.2013.03.043. Epub 2013 Mar 19. Bioorg Med Chem Lett. 2013. PMID: 23735741
Design, structure-activity relationship study and biological evaluation of the thieno[3,2-c]isoquinoline scaffold as a potential anti-cancer agent.
Liu JT, Jaunky DB, Larocque K, Chen F, Mckibbon K, Sirouspour M, Taylor S, Shafeii A, Campbell D, Braga H, Piekny A, Forgione P. Liu JT, et al. Among authors: forgione p. Bioorg Med Chem Lett. 2021 Nov 15;52:128327. doi: 10.1016/j.bmcl.2021.128327. Epub 2021 Aug 18. Bioorg Med Chem Lett. 2021. PMID: 34416378
69 results