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Alpha-galactosylceramide improves the potency of mRNA LNP vaccines against cancer and intracellular bacteria.
Meulewaeter S, Aernout I, Deprez J, Engelen Y, De Velder M, Franceschini L, Breckpot K, Van Calenbergh S, Asselman C, Boucher K, Impens F, De Smedt SC, Verbeke R, Lentacker I. Meulewaeter S, et al. Among authors: franceschini l. J Control Release. 2024 Jun;370:379-391. doi: 10.1016/j.jconrel.2024.04.052. Epub 2024 May 4. J Control Release. 2024. PMID: 38697317 Free article.
A synthetic DNA template for fast manufacturing of versatile single epitope mRNA.
de Mey W, De Schrijver P, Autaers D, Pfitzer L, Fant B, Locy H, Esprit A, Lybaert L, Bogaert C, Verdonck M, Thielemans K, Breckpot K, Franceschini L. de Mey W, et al. Among authors: franceschini l. Mol Ther Nucleic Acids. 2022 Aug 17;29:943-954. doi: 10.1016/j.omtn.2022.08.021. eCollection 2022 Sep 13. Mol Ther Nucleic Acids. 2022. PMID: 36159589 Free PMC article.
An mRNA mix redirects dendritic cells towards an antiviral program, inducing anticancer cytotoxic stem cell and central memory CD8+ T cells.
de Mey W, Locy H, De Ridder K, De Schrijver P, Autaers D, Lakdimi A, Esprit A, Franceschini L, Thielemans K, Verdonck M, Breckpot K. de Mey W, et al. Among authors: franceschini l. Front Immunol. 2023 Feb 13;14:1111523. doi: 10.3389/fimmu.2023.1111523. eCollection 2023. Front Immunol. 2023. PMID: 36860873 Free PMC article.
Neo-Antigen mRNA Vaccines.
Esprit A, de Mey W, Bahadur Shahi R, Thielemans K, Franceschini L, Breckpot K. Esprit A, et al. Among authors: franceschini l. Vaccines (Basel). 2020 Dec 18;8(4):776. doi: 10.3390/vaccines8040776. Vaccines (Basel). 2020. PMID: 33353155 Free PMC article. Review.
165 results