Tutt A - Search Results

1

Agonist anti-human CD27 monoclonal antibody induces T cell activation and tumor immunity in human CD27-transgenic mice.

He LZ, Prostak N, Thomas LJ, Vitale L, Weidlick J, Crocker A, Pilsmaker CD, Round SM, Tutt A, Glennie MJ, Marsh H, Keler T. He LZ, et al. Among authors: tutt a. J Immunol. 2013 Oct 15;191(8):4174-83. doi: 10.4049/jimmunol.1300409. Epub 2013 Sep 11. J Immunol. 2013. PMID: 24026078

2

T cell immunity to lymphoma following treatment with anti-CD40 monoclonal antibody.

Tutt AL, O'Brien L, Hussain A, Crowther GR, French RR, Glennie MJ. Tutt AL, et al. J Immunol. 2002 Mar 15;168(6):2720-8. doi: 10.4049/jimmunol.168.6.2720. J Immunol. 2002. PMID: 11884438

3

Control of established melanoma by CD27 stimulation is associated with enhanced effector function and persistence, and reduced PD-1 expression of tumor infiltrating CD8(+) T cells.

Roberts DJ, Franklin NA, Kingeter LM, Yagita H, Tutt AL, Glennie MJ, Bullock TN. Roberts DJ, et al. Among authors: tutt al. J Immunother. 2010 Oct;33(8):769-79. doi: 10.1097/CJI.0b013e3181ee238f. J Immunother. 2010. PMID: 20842060 Free PMC article.

4

Immunotherapy targeting inhibitory Fcγ receptor IIB (CD32b) in the mouse is limited by monoclonal antibody consumption and receptor internalization.

Williams EL, Tutt AL, Beers SA, French RR, Chan CH, Cox KL, Roghanian A, Penfold CA, Butts CL, Boross P, Verbeek JS, Cragg MS, Glennie MJ. Williams EL, et al. Among authors: tutt al. J Immunol. 2013 Oct 15;191(8):4130-40. doi: 10.4049/jimmunol.1301430. Epub 2013 Sep 11. J Immunol. 2013. PMID: 24026082

5

Activation and preferential expansion of rat cytotoxic (CD8) T cells in vitro and in vivo with a bispecific (anti-TCR alpha/beta x anti-CD2) F(ab')2 antibody.

Tutt AL, Reid R, Wilkins BS, Glennie MJ. Tutt AL, et al. J Immunol. 1995 Sep 15;155(6):2960-71. J Immunol. 1995. PMID: 7673714

6

Trispecific F(ab')3 derivatives that use cooperative signaling via the TCR/CD3 complex and CD2 to activate and redirect resting cytotoxic T cells.

Tutt A, Stevenson GT, Glennie MJ. Tutt A, et al. J Immunol. 1991 Jul 1;147(1):60-9. J Immunol. 1991. PMID: 1675655

7

Eradication of lymphoma by CD8 T cells following anti-CD40 monoclonal antibody therapy is critically dependent on CD27 costimulation.

French RR, Taraban VY, Crowther GR, Rowley TF, Gray JC, Johnson PW, Tutt AL, Al-Shamkhani A, Glennie MJ. French RR, et al. Among authors: tutt al. Blood. 2007 Jun 1;109(11):4810-5. doi: 10.1182/blood-2006-11-057216. Epub 2007 Feb 20. Blood. 2007. PMID: 17311995 Free article.

8

CD11c provides an effective immunotarget for the generation of both CD4 and CD8 T cell responses.

Castro FV, Tutt AL, White AL, Teeling JL, James S, French RR, Glennie MJ. Castro FV, et al. Eur J Immunol. 2008 Aug;38(8):2263-73. doi: 10.1002/eji.200838302. Eur J Immunol. 2008. PMID: 18651710 Free article.

9

Systemic inflammation modulates Fc receptor expression on microglia during chronic neurodegeneration.

Lunnon K, Teeling JL, Tutt AL, Cragg MS, Glennie MJ, Perry VH. Lunnon K, et al. J Immunol. 2011 Jun 15;186(12):7215-24. doi: 10.4049/jimmunol.0903833. Epub 2011 May 13. J Immunol. 2011. PMID: 21572034 Free article.

10

Interaction with FcγRIIB is critical for the agonistic activity of anti-CD40 monoclonal antibody.

White AL, Chan HT, Roghanian A, French RR, Mockridge CI, Tutt AL, Dixon SV, Ajona D, Verbeek JS, Al-Shamkhani A, Cragg MS, Beers SA, Glennie MJ. White AL, et al. Among authors: tutt al. J Immunol. 2011 Aug 15;187(4):1754-63. doi: 10.4049/jimmunol.1101135. Epub 2011 Jul 8. J Immunol. 2011. PMID: 21742972

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