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A hormone-DNA repair circuit governs the response to genotoxic insult.
Goodwin JF, Schiewer MJ, Dean JL, Schrecengost RS, de Leeuw R, Han S, Ma T, Den RB, Dicker AP, Feng FY, Knudsen KE. Goodwin JF, et al. Among authors: dean jl. Cancer Discov. 2013 Nov;3(11):1254-71. doi: 10.1158/2159-8290.CD-13-0108. Epub 2013 Sep 11. Cancer Discov. 2013. PMID: 24027197 Free PMC article.
Dual roles of PARP-1 promote cancer growth and progression.
Schiewer MJ, Goodwin JF, Han S, Brenner JC, Augello MA, Dean JL, Liu F, Planck JL, Ravindranathan P, Chinnaiyan AM, McCue P, Gomella LG, Raj GV, Dicker AP, Brody JR, Pascal JM, Centenera MM, Butler LM, Tilley WD, Feng FY, Knudsen KE. Schiewer MJ, et al. Among authors: dean jl. Cancer Discov. 2012 Dec;2(12):1134-49. doi: 10.1158/2159-8290.CD-12-0120. Epub 2012 Sep 19. Cancer Discov. 2012. PMID: 22993403 Free PMC article.
USP22 regulates oncogenic signaling pathways to drive lethal cancer progression.
Schrecengost RS, Dean JL, Goodwin JF, Schiewer MJ, Urban MW, Stanek TJ, Sussman RT, Hicks JL, Birbe RC, Draganova-Tacheva RA, Visakorpi T, DeMarzo AM, McMahon SB, Knudsen KE. Schrecengost RS, et al. Among authors: dean jl. Cancer Res. 2014 Jan 1;74(1):272-86. doi: 10.1158/0008-5472.CAN-13-1954. Epub 2013 Nov 6. Cancer Res. 2014. PMID: 24197134 Free PMC article.
DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis.
Goodwin JF, Kothari V, Drake JM, Zhao S, Dylgjeri E, Dean JL, Schiewer MJ, McNair C, Jones JK, Aytes A, Magee MS, Snook AE, Zhu Z, Den RB, Birbe RC, Gomella LG, Graham NA, Vashisht AA, Wohlschlegel JA, Graeber TG, Karnes RJ, Takhar M, Davicioni E, Tomlins SA, Abate-Shen C, Sharifi N, Witte ON, Feng FY, Knudsen KE. Goodwin JF, et al. Among authors: dean jl. Cancer Cell. 2015 Jul 13;28(1):97-113. doi: 10.1016/j.ccell.2015.06.004. Cancer Cell. 2015. PMID: 26175416 Free PMC article.
RB Loss Promotes Prostate Cancer Metastasis.
Thangavel C, Boopathi E, Liu Y, Haber A, Ertel A, Bhardwaj A, Addya S, Williams N, Ciment SJ, Cotzia P, Dean JL, Snook A, McNair C, Price M, Hernandez JR, Zhao SG, Birbe R, McCarthy JB, Turley EA, Pienta KJ, Feng FY, Dicker AP, Knudsen KE, Den RB. Thangavel C, et al. Among authors: dean jl. Cancer Res. 2017 Feb 15;77(4):982-995. doi: 10.1158/0008-5472.CAN-16-1589. Epub 2016 Dec 6. Cancer Res. 2017. PMID: 27923835 Free PMC article.
Convergence of oncogenic and hormone receptor pathways promotes metastatic phenotypes.
Augello MA, Burd CJ, Birbe R, McNair C, Ertel A, Magee MS, Frigo DE, Wilder-Romans K, Shilkrut M, Han S, Jernigan DL, Dean JL, Fatatis A, McDonnell DP, Visakorpi T, Feng FY, Knudsen KE. Augello MA, et al. Among authors: dean jl. J Clin Invest. 2013 Jan;123(1):493-508. doi: 10.1172/JCI64750. Epub 2012 Dec 21. J Clin Invest. 2013. PMID: 23257359 Free PMC article.
Consequence of the tumor-associated conversion to cyclin D1b.
Augello MA, Berman-Booty LD, Carr R 3rd, Yoshida A, Dean JL, Schiewer MJ, Feng FY, Tomlins SA, Gao E, Koch WJ, Benovic JL, Diehl JA, Knudsen KE. Augello MA, et al. Among authors: dean jl. EMBO Mol Med. 2015 May;7(5):628-47. doi: 10.15252/emmm.201404242. EMBO Mol Med. 2015. PMID: 25787974 Free PMC article.
110 results