Alexopoulos LG - Search Results

1

Detecting and removing inconsistencies between experimental data and signaling network topologies using integer linear programming on interaction graphs.

Melas IN, Samaga R, Alexopoulos LG, Klamt S. Melas IN, et al. Among authors: alexopoulos lg. PLoS Comput Biol. 2013;9(9):e1003204. doi: 10.1371/journal.pcbi.1003204. Epub 2013 Sep 5. PLoS Comput Biol. 2013. PMID: 24039561 Free PMC article.

2

The logic of EGFR/ErbB signaling: theoretical properties and analysis of high-throughput data.

Samaga R, Saez-Rodriguez J, Alexopoulos LG, Sorger PK, Klamt S. Samaga R, et al. Among authors: alexopoulos lg. PLoS Comput Biol. 2009 Aug;5(8):e1000438. doi: 10.1371/journal.pcbi.1000438. Epub 2009 Aug 7. PLoS Comput Biol. 2009. PMID: 19662154 Free PMC article.

3

Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction.

Saez-Rodriguez J, Alexopoulos LG, Epperlein J, Samaga R, Lauffenburger DA, Klamt S, Sorger PK. Saez-Rodriguez J, et al. Among authors: alexopoulos lg. Mol Syst Biol. 2009;5:331. doi: 10.1038/msb.2009.87. Epub 2009 Dec 1. Mol Syst Biol. 2009. PMID: 19953085 Free PMC article.

4

Identifying drug effects via pathway alterations using an integer linear programming optimization formulation on phosphoproteomic data.

Mitsos A, Melas IN, Siminelakis P, Chairakaki AD, Saez-Rodriguez J, Alexopoulos LG. Mitsos A, et al. Among authors: alexopoulos lg. PLoS Comput Biol. 2009 Dec;5(12):e1000591. doi: 10.1371/journal.pcbi.1000591. Epub 2009 Dec 4. PLoS Comput Biol. 2009. PMID: 19997482 Free PMC article.

5

Construction of signaling pathways and identification of drug effects on the liver cancer cell HepG2.

Alexopoulos LG, Melas IN, Chairakaki AD, Saez-Rodriguez J, Mitsos A. Alexopoulos LG, et al. Annu Int Conf IEEE Eng Med Biol Soc. 2010;2010:6717-20. doi: 10.1109/IEMBS.2010.5626246. Annu Int Conf IEEE Eng Med Biol Soc. 2010. PMID: 21096084

6

Combined logical and data-driven models for linking signalling pathways to cellular response.

Melas IN, Mitsos A, Messinis DE, Weiss TS, Alexopoulos LG. Melas IN, et al. Among authors: alexopoulos lg. BMC Syst Biol. 2011 Jul 5;5:107. doi: 10.1186/1752-0509-5-107. BMC Syst Biol. 2011. PMID: 21729292 Free PMC article.

7

Large-scale network models of IL-1 and IL-6 signalling and their hepatocellular specification.

Ryll A, Samaga R, Schaper F, Alexopoulos LG, Klamt S. Ryll A, et al. Among authors: alexopoulos lg. Mol Biosyst. 2011 Dec;7(12):3253-70. doi: 10.1039/c1mb05261f. Epub 2011 Oct 3. Mol Biosyst. 2011. PMID: 21968890

8

Modeling signaling pathways in articular cartilage.

Melas IN, Chairakaki AD, Mitsos A, Dailiana Z, Provatidis CG, Alexopoulos LG. Melas IN, et al. Among authors: alexopoulos lg. Annu Int Conf IEEE Eng Med Biol Soc. 2011;2011:3712-5. doi: 10.1109/IEMBS.2011.6090630. Annu Int Conf IEEE Eng Med Biol Soc. 2011. PMID: 22255146

9

Construction of large signaling pathways using an adaptive perturbation approach with phosphoproteomic data.

Melas IN, Mitsos A, Messinis DE, Weiss TS, Rodriguez JS, Alexopoulos LG. Melas IN, et al. Among authors: alexopoulos lg. Mol Biosyst. 2012 Apr;8(5):1571-84. doi: 10.1039/c2mb05482e. Epub 2012 Mar 23. Mol Biosyst. 2012. PMID: 22446821

10

Non Linear Programming (NLP) formulation for quantitative modeling of protein signal transduction pathways.

Mitsos A, Melas IN, Morris MK, Saez-Rodriguez J, Lauffenburger DA, Alexopoulos LG. Mitsos A, et al. Among authors: alexopoulos lg. PLoS One. 2012;7(11):e50085. doi: 10.1371/journal.pone.0050085. Epub 2012 Nov 30. PLoS One. 2012. PMID: 23226239 Free PMC article.

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