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Evaluation of repeat administration of a replication deficient, recombinant adenovirus containing the normal cystic fibrosis transmembrane conductance regulator cDNA to the airways of individuals with cystic fibrosis.
Crystal RG, Mastrangeli A, Sanders A, Cooke J, King T, Gilbert F, Henschke C, Pascal W, Herena J, Harvey BG, et al. Crystal RG, et al. Hum Gene Ther. 1995 May;6(5):667-703. doi: 10.1089/hum.1995.6.5-667. Hum Gene Ther. 1995. PMID: 7578402 No abstract available.
Phase I study of direct administration of a replication deficient adenovirus vector containing the E. coli cytosine deaminase gene to metastatic colon carcinoma of the liver in association with the oral administration of the pro-drug 5-fluorocytosine.
Crystal RG, Hirschowitz E, Lieberman M, Daly J, Kazam E, Henschke C, Yankelevitz D, Kemeny N, Silverstein R, Ohwada A, Russi T, Mastrangeli A, Sanders A, Cooke J, Harvey BG. Crystal RG, et al. Hum Gene Ther. 1997 May 20;8(8):985-1001. doi: 10.1089/hum.1997.8.8-985. Hum Gene Ther. 1997. PMID: 9195221 Clinical Trial. No abstract available.
Airway epithelial CFTR mRNA expression in cystic fibrosis patients after repetitive administration of a recombinant adenovirus.
Harvey BG, Leopold PL, Hackett NR, Grasso TM, Williams PM, Tucker AL, Kaner RJ, Ferris B, Gonda I, Sweeney TD, Ramalingam R, Kovesdi I, Shak S, Crystal RG. Harvey BG, et al. Among authors: crystal rg. J Clin Invest. 1999 Nov;104(9):1245-55. doi: 10.1172/JCI7935. J Clin Invest. 1999. PMID: 10545523 Free PMC article. Clinical Trial.
914 results